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一名65岁患者的卵巢浆液性囊腺瘤伴异位肾上腺组织:病例报告

Ovarian serous cystadenoma with ectopic adrenal tissue in a 65-year-old patient: A case report.

作者信息

Şahin Çağdaş, Taylan Enes, Akdemir Ali, Zekioglu Osman, Seyidova Parvane, Ergenoglu Ahmet Mete

机构信息

Department of Obstetrics and Gynecology, Ege University School of Medicine, Izmir, Turkey.

Department of Obstetrics and Gynecology, Ege University School of Medicine, Izmir, Turkey.

出版信息

Int J Surg Case Rep. 2017;33:89-91. doi: 10.1016/j.ijscr.2017.02.045. Epub 2017 Feb 27.

Abstract

INTRODUCTION

Ectopic adrenal tissue is a very rare entity in adult females, especially in the ovary, and is generally diagnosed incidentally during surgery. Although it can present at various sites during childhood, it becomes atrophic by adulthood due to normally functioning adrenal glands. Patients are predominantly asymptomatic; however, in some cases endocrine symptoms such as hypertension and fasciotruncal obesity due to hormonal activity can be seen or neoplastic transformation can appear.

PRESENTATION OF CASE

A 65-year-old patient with progressive pelvic pain and postmenopausal vaginal bleeding was evaluated by transvaginal ultrasound, which revealed bilateral adnexal masses measuring 5cm in size and a normal uterus with an increased endometrial thickness of 7mm. Initially the endometrial sampling result was reported as benign. The patient underwent abdominal hysterectomy and bilateral salpingo-oophorectomy and the pathological diagnosis was again benign, with serous ovarian cystadenoma being found in both ovaries. The pathologist also reported incidental ectopic adrenal tissue on the wall of the left ovarian cystadenoma.

DISCUSSION

Ectopic adrenal tissue is infrequent in female genital organs especially at older ages. Only a few cases of ovarian ectopic adrenal tissue have been reported. To the best of our knowledge the present case is the fourth report in the English literature, and is of additional importance given the patient's age.

CONCLUSION

Ectopic adrenal tissues are generally asymptomatic and revealed incidentally during surgery; however some cases have demonstrated the risk of neoplastic transformation. Therefore, surgeons must be aware of this rare entity that bears the risk of malignancy, and should surgically remove all suspicious lesions.

摘要

引言

异位肾上腺组织在成年女性中非常罕见,尤其是在卵巢中,通常在手术中偶然被诊断出来。虽然它在儿童时期可出现在各个部位,但由于正常功能的肾上腺,到成年时会萎缩。患者大多无症状;然而,在某些情况下,可出现因激素活性导致的高血压和躯干性肥胖等内分泌症状,或发生肿瘤转化。

病例介绍

一名65岁有进行性盆腔疼痛和绝经后阴道出血的患者接受经阴道超声检查,结果显示双侧附件有大小为5厘米的肿块,子宫正常,子宫内膜厚度增加至7毫米。最初子宫内膜取样结果报告为良性。患者接受了腹式子宫切除术和双侧输卵管卵巢切除术,病理诊断再次为良性,双侧卵巢均发现浆液性卵巢囊腺瘤。病理学家还报告在左侧卵巢囊腺瘤壁上偶然发现异位肾上腺组织。

讨论

异位肾上腺组织在女性生殖器官中很少见,尤其是在老年患者中。仅报道过少数几例卵巢异位肾上腺组织病例。据我们所知,本病例是英文文献中的第四例报告,鉴于患者年龄,具有额外的重要性。

结论

异位肾上腺组织通常无症状,在手术中偶然发现;然而,一些病例已显示出肿瘤转化的风险。因此,外科医生必须意识到这种具有恶性风险的罕见实体,应手术切除所有可疑病变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe7b/5350495/1819d9507ebd/gr1.jpg

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