Ferreira Caroline W S, Atan Ixora K, Martin Andrew, Shek Ka Lai, Dietz Hans Peter
Departamento de Fisioterapia, Universidade Federal de Pernambuco, Av. Prof. Moraes Rego, 1235, Cidade Universitária, Recife, Pernambuco, Brazil, CEP:50670-901.
Universiti Kebangsaan, Kuala Lumpur, Malaysia.
Int Urogynecol J. 2017 Oct;28(10):1499-1505. doi: 10.1007/s00192-017-3297-4. Epub 2017 Mar 11.
Female pelvic organ prolapse is highly prevalent and childbirth has been shown to be an important risk factor. The study was carried out to observe if pelvic organ support deteriorates over time following a first birth.
This is a retrospective review using archived data sets of women seen in the context of two prospective perinatal imaging studies. All subjects had undergone a standardised interview, a clinical examination and 4D translabial ultrasound, 3 months and 2-5 years post-partum. Main outcome measures were pelvic organ descent and hiatal area at maximum Valsalva manoeuvre. Means at the two time points were compared using paired Student's t test. Predictors of change over time in continuous variables were explored using linear modelling methods.
A total of 300 women had at least two postnatal follow-ups. They were first seen on average 0.39 (SD 0.2, range 0.2-2.1) years and again 3.1 (SD 1.5, range 1.4-8) years after the index delivery, with a mean interval of 2.71 (SD 1.5, range 0.7-7.7) years, providing a total of 813 (300 × 2.71) woman-years of observation. On univariate analysis, there was a significant decrease in mobility over time of the bladder neck, bladder, and rectal ampulla (P = < 0.004) and hiatal area (P = 0.012). The degree of improvement was less marked in women with levator avulsion.
A significant reduction in pelvic organ descent and hiatal area was noted over a mean of 2.7 years after a first birth.
女性盆腔器官脱垂非常普遍,且分娩已被证明是一个重要的危险因素。本研究旨在观察首次分娩后盆腔器官支持功能是否会随时间推移而恶化。
这是一项回顾性研究,使用了两项前瞻性围产期影像学研究中收集的女性存档数据集。所有受试者在产后3个月和2 - 5年时均接受了标准化访谈、临床检查以及经阴唇4D超声检查。主要观察指标为最大Valsalva动作时盆腔器官的下降程度和裂孔面积。使用配对t检验比较两个时间点的均值。采用线性建模方法探索连续变量随时间变化的预测因素。
共有300名女性至少进行了两次产后随访。她们首次就诊的平均时间为产后0.39(标准差0.2,范围0.2 - 2.1)年,再次就诊时间为产后3.1(标准差1.5,范围1.4 - 8)年,平均间隔为2.71(标准差1.5,范围0.7 - 7.7)年,共提供了813(300×2.71)人年的观察数据。单因素分析显示,膀胱颈、膀胱和直肠壶腹的活动度随时间显著降低(P < 0.004),裂孔面积也显著降低(P = 0.012)。提肌撕裂的女性改善程度不太明显。
首次分娩后平均2.7年,盆腔器官下降程度和裂孔面积显著减小。