腹膜后纤维化、麦角新碱与恶性淋巴瘤。
Retroperitoneal fibrosis, methysergide and malignant lymphoma.
作者信息
Hurley B P, Macarthur E B, Utley G L
出版信息
Aust N Z J Med. 1978 Aug;8(4):417-9. doi: 10.1111/j.1445-5994.1978.tb04914.x.
Abstract
A patient who developed retroperitoneal fibrosis on low dose continuous methysergide therapy is presented. Discontinuing the drug led to rapid clinical improvement but the patient was subsequently found to have disseminated malignant lymphoma. This may have had a synergistic effect with methysergide in producing retroperitoneal fibrosis. The patient had also previously had thyrotoxicosis but no evidence of a continuing autoimmune process was found.
摘要
本文报告了一名在接受低剂量连续美西麦角治疗时发生腹膜后纤维化的患者。停用该药物后临床症状迅速改善，但该患者随后被发现患有弥漫性恶性淋巴瘤。这可能与美西麦角在导致腹膜后纤维化方面具有协同作用。该患者既往还曾患甲状腺毒症，但未发现持续自身免疫过程的证据。
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