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急诊科严重脓毒症和感染性休克管理的方案依从性;一项临床审计

Protocol Adherence for Severe Sepsis and Septic Shock Management in the Emergency Department; a Clinical Audit.

作者信息

Alavi-Moghaddam Mostafa, Anvari Ali, Soltani Delgosha Reaza, Kariman Hamid

机构信息

Emergency Department, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Emergency Department, Shohadaye Pakdasht Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Emerg (Tehran). 2017;5(1):e16. Epub 2017 Jan 9.

Abstract

INTRODUCTION

Although significant development in the field of medicine is achieved, sepsis is still a major issue threatening humans' lives. This study was aimed to audit the management of severe sepsis and septic shock patients in emergency department (ED) according to the present standard guidelines.

METHOD

This is a prospective audit on approaching adult septic patients who were admitted to ED. The audit checklist was created based on the protocols of Surviving Sepsis Campaign and British Royal College recommendations. The mean knowledge score and the compliance rate of studied measures regarding standard protocols were calculated using SPSS version 21.

RESULTS

30 emergency medicine residents were audited (63.3% male). The mean knowledge score of studied residents regarding standard guidelines were 5.07 ± 1.78 (IQR = 2) in pre education and 8.17 ± 1.31 (IQR = 85) in post education phase (p < 0.001). There was excellent compliance with standard in 4 (22%) studied measures, good in 2 (11%), fair in 1 (6%), weak in 2 (11%), and poor in 9 (50%). 64% of poor compliance measures correlated to therapeutic factors. After training, score of 5 measures including checking vital signs in < 20 minute, central vein pressure measurement in < 1 hour, blood culture request, administration of vasopressor agents, and high flow O therapy were improved clinically, but not statistically.

CONCLUSION

The protocol adherence in management of severe sepsis and septic shock for urine output measurement, central venous pressure monitoring, administration of inotrope agents, blood transfusion, intravenous antibiotic and hydration therapy, and high flow O delivery were disappointingly low. It seems training workshops and implementation of Clinical audit can improve residents' adherence to current standard guidelines regarding severe sepsis and septic shock.

摘要

引言

尽管医学领域取得了重大进展,但脓毒症仍是威胁人类生命的主要问题。本研究旨在根据现行标准指南审核急诊科(ED)中严重脓毒症和脓毒性休克患者的管理情况。

方法

这是一项对入住ED的成年脓毒症患者进行的前瞻性审核。审核清单是根据拯救脓毒症运动的方案和英国皇家学院的建议制定的。使用SPSS 21版计算研究措施关于标准方案的平均知识得分和依从率。

结果

对30名急诊医学住院医师进行了审核(男性占63.3%)。研究对象住院医师在教育前关于标准指南的平均知识得分为5.07±1.78(四分位间距=2),在教育后阶段为8.17±1.31(四分位间距=85)(p<0.001)。在研究的措施中,4项(22%)对标准的依从性极佳,2项(11%)良好,1项(6%)中等,2项(11%)较弱,9项(50%)较差。64%的依从性差的措施与治疗因素相关。培训后,包括在<20分钟内检查生命体征、在<1小时内测量中心静脉压、申请血培养、使用血管升压药以及高流量氧疗在内的5项措施的得分在临床上有所提高,但无统计学意义。

结论

在严重脓毒症和脓毒性休克管理中,对于尿量测量、中心静脉压监测、使用血管活性药物、输血、静脉抗生素和补液治疗以及高流量氧输送的方案依从性低得令人失望。培训讲习班和临床审核的实施似乎可以提高住院医师对严重脓毒症和脓毒性休克现行标准指南的依从性。

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