Kartha V N, Krishnamurthy S
Indian J Physiol Pharmacol. 1978 Jan-Mar;22(1):44-52.
Peroxidation of the unsaturated lipid of tissue homogenates is an established method to assess the antioxidant or vitamin E status of animals. In the present study the spontaneous lipid peroxidation in air of rat brain homogenates is reported. The effects of various factors like pH, time, concentration of tissues, temperature, ferrocompounds and catalysis by added tissues like liver are described. Rat brain homogenates appear to be a suitable preparation for in vitro studies of lipid peroxidation.
组织匀浆中不饱和脂质的过氧化是评估动物抗氧化或维生素E状态的既定方法。在本研究中,报告了大鼠脑匀浆在空气中的自发脂质过氧化情况。描述了各种因素的影响,如pH值、时间、组织浓度、温度、铁化合物以及肝脏等添加组织的催化作用。大鼠脑匀浆似乎是脂质过氧化体外研究的合适制剂。