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从猪垂体中分离和鉴定促肾上腺皮质激素相关肽

Isolation and characterization of ACTH-related peptides from porcine pituitaries.

作者信息

Voigt K, Stegmaier W

机构信息

Institut für Klinische Pharmakologie, Freie Universität, Berlin, F.R.G.

出版信息

NIDA Res Monogr. 1986;75:279-82.

PMID:2828977
Abstract

We report on the isolation of new variants of porcine ACTH with corticotropic activity. Two of these variants differ in their amino acid sequence from porcine ACTH at one position (Arg8). This implies that they cannot be derived from the known precursor proopiomelanocortin (POMC).

摘要

我们报告了具有促肾上腺皮质激素活性的猪促肾上腺皮质激素新变体的分离情况。其中两个变体在一个位置（精氨酸8）的氨基酸序列与猪促肾上腺皮质激素不同。这意味着它们不可能来自已知的前体阿黑皮素原（POMC）。

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