Krüger T H C, Kneer J
Arbeitsbereich Klinische Psychologie & Sexualmedizin, Klinik für Psychiatrie, Sozialpsychiatrie, und Psychotherapie, Zentrum für Seelische Gesundheit, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland.
Nervenarzt. 2017 May;88(5):451-458. doi: 10.1007/s00115-017-0300-8.
Sexual functions are regulated by hormonal and neurochemical factors as well as neuronal networks. An understanding of these basic principles is necessary for the diagnostics, counselling and treatment of sexual problems.
Description of essential mechanisms of sexual function on a neurochemical and neuronal level.
Literature search, selection and discussion of relevant studies.
Analogous to the dual control model there are primary inhibitory (e. g. serotonin) and excitatory neurotransmitter systems (e.g. sex steroids and dopamine). Moreover, neuronal structures have been identified that are responsible for processing sexual stimuli. These networks are altered in subjects with sexual disorders or by pharmacological treatment, e. g. antiandrogens and selective serotonin reuptake inhibitors (SSRI) CONCLUSION: Knowledge of the neurobiology of sexuality forms the foundations for the treatment of sexual dysfunctions in psychiatry and other disciplines.
性功能受激素、神经化学因素以及神经网络调节。了解这些基本原理对于性功能障碍的诊断、咨询和治疗至关重要。
在神经化学和神经元水平描述性功能的基本机制。
文献检索、相关研究的筛选与讨论。
类似于双重控制模型，存在主要的抑制性（如血清素）和兴奋性神经递质系统（如性类固醇和多巴胺）。此外，已确定负责处理性刺激的神经元结构。在患有性功能障碍的个体或通过药物治疗（如抗雄激素和选择性5-羟色胺再摄取抑制剂）后，这些网络会发生改变。结论：性神经生物学知识为精神病学及其他学科中性功能障碍的治疗奠定了基础。
