一种新型综合阿片受体模型。
A novel comprehensive opiate-receptor model.
作者信息
Kolb V M, Snyder J P
机构信息
Department of Chemistry, University of Wisconsin-Parkside, Kenosha 53141.
出版信息
NIDA Res Monogr. 1986;75:41-4.
PMID:2828987
Abstract
A new, comprehensive opiate-receptor model based on calculations of possible events at the molecular level is proposed. Agonist versus antagonist action, ultra long-lasting activity and N-dealkylation accompanying receptor binding are included.
摘要
提出了一种基于分子水平上可能事件计算的全新综合阿片受体模型。该模型涵盖了激动剂与拮抗剂作用、超长持续活性以及伴随受体结合的N-脱烷基化。
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