肺北京诺卡菌感染与多发性硬化症患者使用阿仑单抗有关。
Pulmonary Nocardia beijingensis infection associated with the use of alemtuzumab in a patient with multiple sclerosis.
机构信息
Department of Pharmacy Practice, Lebanese American University, Beirut, Lebanon.
Department of Internal Medicine, UAB School of Medicine, Huntsville, AL, USA.
出版信息
Mult Scler. 2017 May;23(6):872-874. doi: 10.1177/1352458517694431. Epub 2017 Feb 1.
PMID:28290754
Abstract
Nocardia is a Gram-positive aerobic pathogen that usually affects immunocompromised patients. We report a case of pulmonary infection caused by a rare Nocardia species, Nocardia beijingensis, in a 50-year-old woman who had received alemtuzumab for the treatment of her multiple sclerosis. The invasive pulmonary infection was successfully treated with meropenem.
摘要
诺卡菌是一种革兰阳性需氧病原体，通常影响免疫功能低下的患者。我们报告了一例由罕见的诺卡菌属，北京诺卡菌引起的 50 岁女性肺部感染病例。该患者患有多发性硬化症，曾接受阿仑单抗治疗。侵袭性肺部感染经美罗培南治疗后成功治愈。
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