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Denosumab and surgery for the treatment of Perthes' disease in a 9-year-old boy: favorable course documented by comprehensive imaging- a case report.

作者信息

Meiss A Ludwig, Barvencik Florian, Babin Kornelia, Eggers-Stroeder Gerald

机构信息

a Orthopaedicum-Hamburg.

b Department of Osteology and Biomechanics , University Medical Center Hamburg-Eppendorf.

出版信息

Acta Orthop. 2017 Jun;88(3):354-357. doi: 10.1080/17453674.2017.1298020. Epub 2017 Mar 14.

DOI:10.1080/17453674.2017.1298020
PMID:28290756
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5434609/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e651/5434609/e8518534114b/iort-88-354.F08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e651/5434609/d602c66f57b5/iort-88-354.F01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e651/5434609/eea1bd81707d/iort-88-354.F02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e651/5434609/eb96818ca76b/iort-88-354.F03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e651/5434609/9575134a5c80/iort-88-354.F04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e651/5434609/bb0fca98ac17/iort-88-354.F05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e651/5434609/4cdbb7fed7e1/iort-88-354.F06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e651/5434609/387c50a55c77/iort-88-354.F07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e651/5434609/e8518534114b/iort-88-354.F08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e651/5434609/d602c66f57b5/iort-88-354.F01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e651/5434609/eea1bd81707d/iort-88-354.F02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e651/5434609/eb96818ca76b/iort-88-354.F03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e651/5434609/9575134a5c80/iort-88-354.F04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e651/5434609/bb0fca98ac17/iort-88-354.F05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e651/5434609/4cdbb7fed7e1/iort-88-354.F06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e651/5434609/387c50a55c77/iort-88-354.F07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e651/5434609/e8518534114b/iort-88-354.F08.jpg

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1
Denosumab and surgery for the treatment of Perthes' disease in a 9-year-old boy: favorable course documented by comprehensive imaging- a case report.地诺单抗与手术治疗一名9岁男孩的佩特兹病:综合影像学记录的良好病程——病例报告
Acta Orthop. 2017 Jun;88(3):354-357. doi: 10.1080/17453674.2017.1298020. Epub 2017 Mar 14.
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A prospective study of nonoperative and operative management for Perthes' disease.一项关于佩特兹病非手术及手术治疗的前瞻性研究。
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[Varization osteotomy in Legg-Perthes-Calvé disease. Apropos of 50 cases].
Rev Chir Orthop Reparatrice Appar Mot. 1976 Jan-Feb;62(1):27-41.
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Legg-Calvé-Perthes' disease.莱-卡-佩三氏病
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[Chiari's pelvic osteotomy in the management of Perthes disease].
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BMJ Case Rep. 2019 Sep 18;12(9):e229919. doi: 10.1136/bcr-2019-229919.

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Safety and efficacy of denosumab in children with osteogenesis imperfect--a first prospective trial.地诺单抗治疗成骨不全患儿的安全性和有效性——一项首次前瞻性试验
J Musculoskelet Neuronal Interact. 2016 Mar;16(1):24-32.
2
Does Zoledronate Prevent Femoral Head Collapse from Osteonecrosis? A Prospective, Randomized, Open-Label, Multicenter Study.唑来膦酸盐能否预防股骨头坏死导致的股骨头塌陷?一项前瞻性、随机、开放标签、多中心研究。
J Bone Joint Surg Am. 2015 Jul 15;97(14):1142-8. doi: 10.2106/JBJS.N.01157.
3
Severe hypercalcemia following denosumab treatment in a juvenile patient.
一名青少年患者在接受地诺单抗治疗后出现严重高钙血症。
J Bone Miner Metab. 2016 Jan;34(1):118-22. doi: 10.1007/s00774-015-0677-z. Epub 2015 Jun 9.
4
Interobserver and intraobserver reliability of the modified Waldenström classification system for staging of Legg-Calvé-Perthes disease.改良的瓦尔登斯特伦分类系统用于莱格-卡尔维-佩特病分期的观察者间和观察者内可靠性。
J Bone Joint Surg Am. 2015 Apr 15;97(8):643-50. doi: 10.2106/JBJS.N.00887.
5
Osteosclerosis induced by denosumab.地诺单抗诱导的骨硬化症。
Lancet. 2015 Feb 7;385(9967):539. doi: 10.1016/S0140-6736(14)61338-6. Epub 2014 Oct 28.
6
Atypical fracture of the femur in a patient using denosumab--a case report.一名使用地诺单抗的患者发生非典型股骨骨折——病例报告。
Acta Orthop. 2014 Feb;85(1):6-7. doi: 10.3109/17453674.2014.885355. Epub 2014 Jan 24.
7
Effects of denosumab treatment and discontinuation on human growth plates.地舒单抗治疗及其停药对人生长板的影响。
J Clin Endocrinol Metab. 2014 Mar;99(3):891-7. doi: 10.1210/jc.2013-3081. Epub 2014 Jan 1.
8
Denosumab and atypical femoral fractures.地诺单抗与非典型股骨骨折
Acta Orthop. 2014 Feb;85(1):1. doi: 10.3109/17453674.2013.859423. Epub 2013 Oct 31.
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Effects of RANK-ligand antibody (denosumab) treatment on bone turnover markers in a girl with juvenile Paget's disease.RANK-ligand 抗体(地舒单抗)治疗对青少年 Pagets 病女性患者骨转换标志物的影响。
J Clin Endocrinol Metab. 2013 Aug;98(8):3121-6. doi: 10.1210/jc.2013-1143. Epub 2013 Jun 20.
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Denosumab: a potential new and innovative treatment option for aneurysmal bone cysts.地舒单抗:动脉瘤样骨囊肿的一种潜在的新型创新治疗选择。
Eur Spine J. 2013 Jun;22(6):1417-22. doi: 10.1007/s00586-013-2715-7. Epub 2013 Mar 1.