Rubanenko O A, Fatenkov O V, Khokhlunov S M, Duplyakov D V
Samara State Medical University, Samara, Russia.
Samara Regional Cardiology Dispensary, Samara, Russia.
Kardiologiia. 2016 Dec;56(11):55-60. doi: 10.18565/cardio.2016.11.55-60.
To identify prevalence of atrial fibrillation (AF) in dependence of volume of coronary artery bypass grafting (CABG) as assessed by the number of grafts.
The study included 431 patients with ischemic heart disease (IHD) who underwent CABG. Group 1 comprised patients with single-vessel bypass graft (n=47, 78.7% men, mean age 59.6+/-5.6 years), group 2 - with multivessel bypass grafts (n=384, 76.8% men, mean age 61.0+/-8,1 years). During the observation period postoperative AF developed in 3 patients (6.4%) with single vessel bypass graft and 69 patients (18.0%) with multivessel bypass grafts. At multivariate analysis predictive values were significant for the following parameters: aortic cross-clamping time >36 min - 1.7 (95% confidence interval [CI], 1.1-3.2, p=0.03), ischemia time >19 min - 2.0 (95% CI, 1.1-3.7, p=0.02), age >59 years - 2.4 (95% CI, 1.3-4.4, p=0.005), left atrial dimension >39 mm - 3.7 (95% CI, 2.1-6.6, p<0.0001), left ventricular ejection fraction <51% - 1.9 (95% CI, 1.3- 3.3, p=0.04). Predictive value of cardiopulmonary bypass time >56 min 1.2 (95% CI, 0.56-2.8) was not significant (p=0.5).
In our study AF in the early postoperative period more often occurred in patients who underwent multivessel coronary bypass surgery. The most powerful predictor of AF in these patients was left atrial dimension exceeding 39 mm.
根据冠状动脉旁路移植术(CABG)的移植物数量评估房颤(AF)的患病率。
该研究纳入了431例行CABG的缺血性心脏病(IHD)患者。第1组为单支血管旁路移植患者(n = 47,男性占78.7%,平均年龄59.6±5.6岁),第2组为多支血管旁路移植患者(n = 384,男性占76.8%,平均年龄61.0±8.1岁)。在观察期内,3例(6.4%)单支血管旁路移植患者和69例(18.0%)多支血管旁路移植患者发生了术后房颤。多因素分析显示,以下参数的预测值具有显著性:主动脉阻断时间>36分钟 - 1.7(95%置信区间[CI],1.1 - 3.2,p = 0.03),缺血时间>19分钟 - 2.0(95%CI,1.1 - 3.7,p = 0.02),年龄>59岁 - 2.4(95%CI,1.3 - 4.4,p = 0.005),左心房内径>39毫米 - 3.7(95%CI,2.1 - 6.6,p<0.0001),左心室射血分数<51% - 1.9(95%CI,1.3 - 3.3,p = 0.04)。体外循环时间>56分钟的预测值为1.2(95%CI,0.56 - 2.8),无显著性差异(p = 0.5)。
在我们的研究中,多支冠状动脉旁路手术患者术后早期房颤的发生率更高。这些患者房颤最有力的预测因素是左心房内径超过39毫米。