Yang Shaolong, Zhao Danhui, Wei Jie, Li Peifeng
Clin Neuropathol. 2017 Jul/Aug;36(4):183-187. doi: 10.5414/NP301014.
Neurogenic neoplasms resulting from autonomic nerves are considerably rare. In this paper, we report a case of a 41-year-old woman with composite tumor of synchronous ganglioneuroma and schwannoma in the vagal inferior ganglion. Ultrasonography and computed tomography showed a well-defined mass, which extruded from the internal and external carotid arteries. Two tumors were closely attached but with an evident boundary. The small tumor was composed of spindle cells and numerous mature ganglion cells, and the large one consisted entirely of differentiated neoplastic Schwann cells. Results showed that these tumors were a schwannoma arising in a ganglioneuroma of the vagal inferior ganglion. Our case is the first to demonstrate the occurrence of schwannoma in benign ganglioneuroma. We also provided clinical and pathological evidence that such transformation can occur spontaneously. .
由自主神经引起的神经源性肿瘤相当罕见。在本文中，我们报告了一例41岁女性病例，其迷走神经下神经节存在神经节神经瘤和神经鞘瘤同步复合肿瘤。超声检查和计算机断层扫描显示一个边界清晰的肿块，该肿块从颈内动脉和颈外动脉之间突出。两个肿瘤紧密相连但边界明显。小肿瘤由梭形细胞和大量成熟神经节细胞组成，大肿瘤完全由分化的肿瘤性施万细胞构成。结果表明，这些肿瘤是起源于迷走神经下神经节神经节神经瘤的神经鞘瘤。我们的病例是首例证明良性神经节神经瘤中发生神经鞘瘤的病例。我们还提供了临床和病理证据，表明这种转变可自发发生。
