Klinik für Augenheilkunde, Universitätsklinikum Freiburg, Deutschland.
Institut für klinische Pathologie, Universitätsklinikum Freiburg, Deutschland.
Klin Monbl Augenheilkd. 2022 Jul;239(7):894-898. doi: 10.1055/a-1806-2405. Epub 2022 Jul 20.
Orbital tumors comprise a variety of diseases, although tumors of the peripheral nerves are rare. Of these, schwannoma is considered the most common entity, consisting histopathologically almost exclusively of Schwann cells. Another benign tumor containing Schwann cells is ganglioneuroma. Here, ganglion cells are histopathologically apparent in addition to the Schwann cell-containing stroma. Ganglioneuroma belongs to the group of neuroblastic tumors and can occur anywhere in the pathway of sympathetic ganglion cells. In this report, we present the disease courses as well as the findings of two patients with different orbital tumors. In both cases, the diagnosis was only confirmed by histopathological examination. The first patient had a schwannoma with cystic degeneration and the second patient had a ganglioneuroma, both tumor entities which occur only rarely in the orbit. Commonalities and differences are discussed.
眼眶肿瘤包括多种疾病，尽管周围神经肿瘤较为罕见。其中，神经鞘瘤被认为是最常见的肿瘤，组织病理学上几乎完全由雪旺细胞组成。另一种含有雪旺细胞的良性肿瘤是神经节细胞瘤。在此，除了含有雪旺细胞的基质外，组织病理学上还可见神经节细胞。神经节细胞瘤属于神经母细胞瘤群，可发生在交感神经节细胞的任何部位。在本报告中，我们介绍了两位患有不同眼眶肿瘤患者的疾病过程和检查结果。两种情况均仅通过组织病理学检查确诊。第一位患者患有伴有囊性变性的神经鞘瘤，第二位患者患有神经节细胞瘤，这两种肿瘤在眼眶中均很少见。讨论了两者的异同。
