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对三个慢性疾病领域中恶病质、消瘦及相关骨骼肌综合征的研究比较。

A comparison of research into cachexia, wasting and related skeletal muscle syndromes in three chronic disease areas.

作者信息

Stewart Coats Andrew J, Shewan Louise G

机构信息

Monash University, Australia; University of Warwick, Coventry, UK.

Monash University, Australia; University of Warwick, Coventry, UK.

出版信息

Int J Cardiol. 2017 May 15;235:33-36. doi: 10.1016/j.ijcard.2017.02.136. Epub 2017 Mar 1.

DOI:10.1016/j.ijcard.2017.02.136
PMID:28291621
Abstract

INTRODUCTION

We compared the frequency of cancer, heart and lung related cachexia and cachexia-related research articles in the specialist journal, Journal of Cachexia, Sarcopenia and Muscle (JCSM) to those seen in a leading European journal in each specialist area during 2015 and 2016 to assess whether work on cachexia and related fields is relatively over or under represented in each specialist area.

RESULTS

In the dedicated journal, Journal of Cachexia, Sarcopenia and Muscle, there were 44 references related to cancer, 5 related to respiratory disease, 5 related to heart failure, and 21 related to more than one of these chronic diseases. Despite this cancer preponderance, in the European Journal of Cancer in the two publication years, there were only 5 relevant publications (0.67% of the journal output), compared to 16 (1.41%) in the European Respiratory Journal and 10 (2.19%) in the European Journal of Heart Failure.

CONCLUSIONS

There is considerable under-representation of cancer cachexia-related papers in the major European Cancer journal despite a high proportion in the dedicated cachexia journal. The under-representation is even more marked when expressed as a percentage, 0.67%, compared to 1.41% and 2.19% of the lung and heart journals respectively. These results are consistent with a worrying lack of interest in, or publication of, cachexia and related syndromes research in the cancer literature in Europe compared to its importance as a clinical syndrome. Greater interest is shown in lung and cardiology journals.

摘要

引言

我们比较了专业期刊《恶病质、肌肉减少症与肌肉杂志》(JCSM)中癌症、心肺相关恶病质以及与恶病质相关的研究文章的频率,与2015年和2016年欧洲各专业领域领先期刊中的情况进行对比,以评估恶病质及相关领域的研究在各专业领域的呈现是相对过多还是过少。

结果

在专门的期刊《恶病质、肌肉减少症与肌肉杂志》中,有44篇参考文献与癌症相关,5篇与呼吸系统疾病相关,5篇与心力衰竭相关,21篇与不止一种这些慢性疾病相关。尽管癌症相关内容占主导,但在这两个出版年份的《欧洲癌症杂志》中,仅有5篇相关出版物(占该期刊产出的0.67%),相比之下,《欧洲呼吸杂志》中有16篇(1.41%),《欧洲心力衰竭杂志》中有10篇(2.19%)。

结论

尽管在专门的恶病质期刊中癌症恶病质相关论文占比很高,但在欧洲主要癌症期刊中此类论文的呈现明显不足。以百分比表示时,这种不足更为明显,分别为0.67%,而肺部和心脏期刊的占比分别为1.41%和2.19%。这些结果表明,与恶病质作为一种临床综合征的重要性相比,欧洲癌症文献中对恶病质及相关综合征研究的兴趣或发表量令人担忧地缺乏。肺部和心脏病学期刊表现出了更大的兴趣。

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