Danieli Maria Giovanna, Gelardi Chiara, Pedini Veronica, Logullo Francesco, Gabrielli Armando
Clinica Medica, Dipartimento di Scienze Cliniche e Molecolari, Universita Politecnica delle Marche & Ospedali Riuniti, Ancona, Italy.
Neurologia, Ospedale Generale Provinciale, Macerata, Italy.
Curr Rheumatol Rev. 2018;14(3):194-199. doi: 10.2174/1573397113666170314120602.
The efficacy of subcutaneous immunoglobulin is reported in several neurological disorders and, more recently, its use has been extended to other inflammatory diseases, such as the idiopathic inflammatory myopathies, including polymyositis and dermatomyositis. Due to the rarity of these disorders, the role of immunoglobulin, administered intravenously or subcutaneously, remains unclear and poorly investigated. We report our experience about the use of subcutaneous immunoglobulin in myositis spectrum disorders, from idiopathic inflammatory myopathies to more complex conditions, such as overlap and cancer-associated myositis or pregnancy.
皮下注射免疫球蛋白在多种神经系统疾病中的疗效已有报道，最近，其应用范围已扩展到其他炎症性疾病，如特发性炎症性肌病，包括多发性肌炎和皮肌炎。由于这些疾病较为罕见，静脉注射或皮下注射免疫球蛋白的作用仍不明确，且研究较少。我们报告了我们在肌炎谱系疾病中使用皮下注射免疫球蛋白的经验，从特发性炎症性肌病到更复杂的情况，如重叠综合征和癌症相关肌炎或妊娠相关肌炎。
