Sampath Kartik, Rothstein Richard I
Section of Gastroenterology and Hepatology, Department of Medicine, Dartmouth-Hitchcock Medical Center, Geisel School of Medicine at Dartmouth, One Medical Center Drive, Lebanon, NH 03756, USA.
Section of Gastroenterology and Hepatology, Department of Medicine, Dartmouth-Hitchcock Medical Center, Geisel School of Medicine at Dartmouth, One Medical Center Drive, Lebanon, NH 03756, USA.
Gastrointest Endosc Clin N Am. 2017 Apr;27(2):267-275. doi: 10.1016/j.giec.2017.01.005.
This article focuses on the stomach target devices that are currently in various stages of development. Approved intragastric balloons, devices targeting small bowel and aspiration techniques, are described in other contributions to this issue. Bariatric endoscopic devices targeting the stomach directly alter gastric physiology and promote weight loss by potentially changing functional gastric volume, gastric emptying, gastric wall compliance, neurohormonal signaling, and, thereby, satiety. Many stomach-targeting devices are on the horizon for clinical use, and further study will determine the safety and efficacy for clinical use.
本文重点关注目前处于不同研发阶段的胃部靶向装置。本期刊物的其他稿件中描述了已获批的胃内气球、针对小肠的装置和抽吸技术。直接针对胃部的减肥内镜装置可通过潜在改变功能性胃容量、胃排空、胃壁顺应性、神经激素信号传导,进而改变饱腹感,直接改变胃生理功能并促进体重减轻。许多靶向胃部的装置即将用于临床,进一步研究将确定其临床使用的安全性和有效性。