Wright Naomi J, Davidson Joseph R, Major Christina, Durkin Natalie, Tan Yew-Wei, Jobson Matthew, Ade-Ajayi Niyi, Hall Nigel J, Bouhadiba Nordeen
Department of Paediatric Surgery, Evelina Children's Hospital, Guy's and St.Thomas' NHS Trust, London, UK; Department of Paediatric Surgery, University Hospital Lewisham, London, UK.
Department of Paediatric Surgery, University Hospital Lewisham, London, UK.
J Pediatr Surg. 2017 Jul;52(7):1108-1112. doi: 10.1016/j.jpedsurg.2017.02.011. Epub 2017 Mar 6.
The optimal management for boys under 3 months of age with an indirect inguinal hernia (IIH) and ipsilateral palpable undescended testis (IPUDT) is unknown. We aimed to: 1) determine the current practice for managing these boys across the UK, and 2) compare outcomes of different treatment strategies.
We undertook two studies. Firstly, we completed a National Survey of all surgeons on the British Association of Paediatric Surgeons email list in 2014. Subsequently, we undertook a multi-centre, retrospective, 10-year (2005-2015) review across 4 pediatric surgery centers of boys under 3months of age with concomitant IIH and IPUDT. Primary outcome was testicular atrophy. Secondary outcomes included need for subsequent orchidopexy, testicular ascent and hernia recurrence. Data are presented as median (range). Chi-squared test and multivariate binomial logistic regression analysis were used for analysis; p<0.05 was considered significant.
Survey: Consultant practice varies widely across the UK, with a tendency towards performing concurrent orchidopexy at the time of herniotomy under 3 months of age. Concurrent orchidopexy is favored less in cases where the hernia is symptomatic. Case Series Review: Forty-one boys with 43 concomitant IIH and IPUDT were identified, and all included. 32 (74%) hernias were reducible, 11 (26%) were symptomatic requiring urgent or emergency repair. Post-conceptual age at surgery was 45weeks (36-65). Primary operations included: 29 (67%) open hernia repair and standard orchidopexy, 8 (19%) open hernia repair with future orchidopexy if required, 4 (9%) laparoscopic hernia repair with future orchidopexy if required, 2 (5%) open hernia repair and suturing of the testis to the inverted scrotum without scrotal incision. Variation in atrophy rate between different surgical approaches did not reach statistical significance (p=0.42). Overall atrophy rate was 18%. If hernia repair alone was undertaken (8 open and 4 laparoscopic), the testis did not descend in 8 patients, requiring subsequent orchidopexy (67%); if orchidopexy was undertaken at the time of hernia repair, 1 in 29 required a repeat orchidopexy (3%) (p=0.0001). No hernia recurred.
This study suggests that orchidopexy at the time of inguinal herniotomy does not increase the risk of testicular atrophy in boys under 3months of age.
3个月以下患有腹股沟斜疝(IIH)和同侧可触及隐睾(IPUDT)的男童的最佳治疗方案尚不清楚。我们的目标是:1)确定英国目前对这些男童的治疗方法,2)比较不同治疗策略的结果。
我们进行了两项研究。首先,2014年我们对英国小儿外科医生协会邮件列表中的所有外科医生进行了全国性调查。随后,我们对4个小儿外科中心10年(2005 - 2015年)间3个月以下同时患有IIH和IPUDT的男童进行了多中心回顾性研究。主要结局是睾丸萎缩。次要结局包括后续是否需要睾丸固定术、睾丸上升和疝气复发。数据以中位数(范围)表示。采用卡方检验和多变量二项式逻辑回归分析进行分析;p<0.05被认为具有统计学意义。
调查:英国各地顾问医生的做法差异很大,倾向于在3个月以下进行疝气修补术时同时进行睾丸固定术。疝气有症状时,同时进行睾丸固定术的倾向较小。病例系列回顾:共确定41名男童,伴有43例IIH和IPUDT,全部纳入研究。32例(74%)疝气可回纳,11例(26%)有症状,需要紧急或急诊修补。手术时的孕龄为45周(36 - 65周)。初次手术包括:29例(67%)开放疝气修补术和标准睾丸固定术,8例(19%)开放疝气修补术,必要时进行二期睾丸固定术,4例(9%)腹腔镜疝气修补术,必要时进行二期睾丸固定术,2例(5%)开放疝气修补术并将睾丸缝合至阴囊而不切开阴囊。不同手术方法之间的萎缩率差异未达到统计学意义(p = 0.42)。总体萎缩率为18%。如果仅进行疝气修补术(8例开放手术和4例腹腔镜手术),则8例患者睾丸未下降,需要后续进行睾丸固定术(67%);如果在疝气修补术时同时进行睾丸固定术,29例中有1例需要再次进行睾丸固定术(3%)(p = 0.0001)。无疝气复发。
本研究表明,3个月以下男童在腹股沟疝气修补术时进行睾丸固定术不会增加睾丸萎缩的风险。