Singh Arun D
Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Br J Ophthalmol. 2017 Nov;101(11):1570-1575. doi: 10.1136/bjophthalmol-2016-310093. Epub 2017 Mar 14.
To describe the technique and results of a minimally invasive surgical technique for resection of small iris lesions.
Consecutive case series of 22 patients with localised, small iris lesions that were resected using the described surgical technique that composed of multiple, small corneal incisions created to allow for internal iris resection with 23-gauge horizontal vitrectomy scissors, followed by guarded tumour aspiration through a clear plastic tubing (diameter 3.5 mm) primed with viscoelastic agent.
The mean largest basal diameter was 3.0 mm (range 1.5-5.0 mm; median 3.0 mm) and mean thickness was 1.3 mm (range 0.5-2.5 mm; median 1.0 mm). Use of multiple (2-4) small corneal incisions (range 2.0-3.0 mm; mean 2.8 mm) allowed reduced postoperative morbidity (significant hyphema (0%), hypotony (0%), wound leak (0%), >2 line change in best corrected visual acuity at postoperative 1 week (4.5%) and mean corneal astigmatism of 1.0 D (range 0.14-2.99 D; median 0.8 D) at postoperative 4-12 weeks. The tumour could be resected with clear surgical margins in all neoplastic cases (benign (2), borderline (1) and malignant (16)). Local recurrence or metastases were not observed in any melanoma case over a mean follow-up of 33.0 months (range 1.0-90.0 months; median 33.5 months).
Small incision guarded hydroaspiration is a minimally invasive surgical technique for resection of select small iris lesions. Use of multiple small corneal incisions avoids morbidity associated with a single large corneoscleral incision, and use of guarded aspiration may eliminate the risk of wound contamination by the malignant tumour.
描述一种用于切除小的虹膜病变的微创手术技术及结果。
对22例局限性小虹膜病变患者进行连续病例系列研究,采用所述手术技术进行切除,该技术包括制作多个小的角膜切口,以便用23号水平玻璃体切割剪刀进行虹膜内切除,然后通过预先注入粘弹性剂的透明塑料导管(直径3.5毫米)进行肿瘤保护性抽吸。
平均最大基底直径为3.0毫米(范围1.5 - 5.0毫米;中位数3.0毫米),平均厚度为1.3毫米(范围0.5 - 2.5毫米;中位数1.0毫米)。使用多个(2 - 4个)小的角膜切口(范围2.0 - 3.0毫米;平均2.8毫米)可降低术后发病率(严重前房积血(0%)、低眼压(0%)、伤口渗漏(0%)、术后1周最佳矫正视力变化>2行(4.5%),术后4 - 12周平均角膜散光为1.0 D(范围0.14 - 2.99 D;中位数0.8 D)。在所有肿瘤病例(良性(2例)、交界性(1例)和恶性(16例))中,肿瘤均可在手术切缘清晰的情况下切除。在平均33.个月(范围1.0 - 90.0个月;中位数33.5个月)的随访中,未观察到任何黑色素瘤病例出现局部复发或转移。
小切口保护性水抽吸术是一种用于切除特定小虹膜病变的微创手术技术。使用多个小的角膜切口可避免与单个大的角巩膜切口相关的发病率,使用保护性抽吸可消除恶性肿瘤污染伤口的风险。