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[血液透析患者血管资本耗竭:结果会怎样?]

[Exhaustion of vascular capital in patients on hemodialysis: what will be the outcome?].

作者信息

Hajji Meriam, Harzallah Amel, Kaaroud Hayet, Jerbi Mona, Chargui Soumaya, Younsi Fethi El, Hamida Fethi Ben, Abdallah Taieb Ben

机构信息

Service de Médecine Interne A, Hôpital Charles Nicolle, Tunis, Tunisie; Laboratoire de Pathologie Rénale LR00SP01, Hôpital Charles Nicolle, Tunis, Tunisie.

Laboratoire de Pathologie Rénale LR00SP01, Hôpital Charles Nicolle, Tunis, Tunisie; Faculté de Médecine de Tunis, université Tunis El Manar, Tunis, Tunisie.

出版信息

Pan Afr Med J. 2016 Dec 19;25:237. doi: 10.11604/pamj.2016.25.237.10665. eCollection 2016.

Abstract

Despite advances in the treatment of chronic renal failure, vascular access remains the weakest link in renal replacement therapy (RRT) and the leading cause of morbidity in patients on hemodialysis We report the case of a young female patient with chronic renal insufficiency secondary to vascular nephropathy on periodic hemodialysis and whose vascular capital was early exhausted due to iterative thromboses in arteriovenous fistulas and failure in peritoneal dialysis. Protein C deficiency was objectified. The patient underwent tunneled hemodialysis catheter insertion at the level of the right atrium via a right anterolateral thoracotomy with cannulation of the inferior vena cava, with poor functional outcome after three months of use. Since then she has been dialyzed using puncture of the external jugular veins.

摘要

尽管慢性肾衰竭的治疗取得了进展,但血管通路仍然是肾脏替代治疗(RRT)中最薄弱的环节,也是血液透析患者发病的主要原因。我们报告了一例年轻女性患者,因血管性肾病继发慢性肾功能不全,需定期进行血液透析,且由于动静脉内瘘反复血栓形成和腹膜透析失败,其血管资源早期就已耗尽。检查发现该患者存在蛋白C缺乏。患者通过右前外侧开胸手术,经右心房在腔静脉插管,置入带隧道的血液透析导管,使用三个月后功能不佳。从那时起,她一直通过穿刺颈外静脉进行透析。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef60/5337301/36d559da6aac/PAMJ-25-237-g001.jpg

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