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[早产儿胃食管反流:一例报告]

[Gastroesophageal reflux in premature: a case report].

作者信息

Ndour Daouda

机构信息

Service de Néonatologie et Réanimation Néonatale, Hôpital d'Enfants Albert Royer de Dakar, Université Cheikh Anta Diop de Dakar, Sénégal.

出版信息

Pan Afr Med J. 2016 Dec 20;25:243. doi: 10.11604/pamj.2016.25.243.10497. eCollection 2016.

Abstract

Gastroesophageal reflux disease (GERD) is a common problem in neonatology. Various physiological protective reflex responses provide a plausible biological link between gastro-esophageal reflux and apnea and bradycardia in premature. It is uncertain whether or not there is a causal relationship between the two diseases. However there is no consensus about the clinical and paraclinical diagnosis. Further explorations and treatment offered to premature infants with symptoms are discussed. We report the case of a preterm infants admitted to neonatal intensive care and with apnea and bradycardia. Clinical examination and exploration results were normal. We retained the gastrointestinal reflux diagnosis complicated of apnea and bradycardia. Pharmacological therapy for gastro-esophageal reflux disease has not definitively been shown to be effective in improving symptoms and should be reserved especially for infants with treatment refractory apnea and bradycardia episodes suspected as being gastro-esophageal reflux in premature infants. From a case report we made a literature review to discuss at length the different aspects of the problem.

摘要

胃食管反流病(GERD)是新生儿科的常见问题。各种生理保护性反射反应为早产儿时胃食管反流与呼吸暂停和心动过缓之间提供了一个合理的生物学联系。这两种疾病之间是否存在因果关系尚不确定。然而,关于临床和辅助临床诊断尚无共识。本文讨论了对有症状的早产儿的进一步探索和治疗。我们报告了一例入住新生儿重症监护病房、患有呼吸暂停和心动过缓的早产儿病例。临床检查和检查结果均正常。我们诊断为胃食管反流并发呼吸暂停和心动过缓。胃食管反流病的药物治疗尚未被明确证明对改善症状有效,尤其应保留用于怀疑因胃食管反流导致治疗难治性呼吸暂停和心动过缓发作的早产儿。通过一个病例报告,我们进行了文献综述以详细讨论该问题的不同方面。

相似文献

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[Gastroesophageal reflux in premature: a case report].[早产儿胃食管反流:一例报告]
Pan Afr Med J. 2016 Dec 20;25:243. doi: 10.11604/pamj.2016.25.243.10497. eCollection 2016.
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Does gastroesophageal reflux cause apnea in preterm infants?胃食管反流会导致早产儿呼吸暂停吗?
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本文引用的文献

7
Multipoint measurement of intragastric pH in healthy preterm infants.健康早产儿胃内pH值的多点测量
Arch Dis Child Fetal Neonatal Ed. 2003 Nov;88(6):F517-20. doi: 10.1136/fn.88.6.f517.
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Can pH monitoring reliably detect gastro-oesophageal reflux in preterm infants?pH监测能否可靠地检测早产儿的胃食管反流?
Arch Dis Child Fetal Neonatal Ed. 2001 Nov;85(3):F155-7; discussion F157-8. doi: 10.1136/fn.85.3.f155.

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