Kehila Mehdi, Halouani Ahmed, Touhami Omar, Abouda Hassine Saber, Khlifi Abdeljalil, Hmid Rim Ben, Benhassen Ines, Masmoudi Aida, Chanoufi Mohamed Badis
Service C du Centre de Maternité et de Néonatologie de Tunis, Faculté de Médecine de Tunis, Université Tunis El Manar, Tunisie.
Service de Gynécologie Obstétrique, CHU Farhat Hached, Faculté de Médecine de Sousse, Tunisie.
Pan Afr Med J. 2016 Dec 21;25:256. doi: 10.11604/pamj.2016.25.256.10011. eCollection 2016.
This study aims to evaluate the value of prenatal ultrasound diagnosis by comparing it with the results of the fetopathological examination in case of therapeutic interruption of pregnancy for fetal indication. We conducted a retrospective descriptive and analytical study carried out over a three-year period from January 2013 to December 2015. It involved 66 fetuses autopsied after therapeutic interruption of pregnancy for fetal indication. Fetopathological examination confirmed ultrasound results in 63 cases (95.4%). In 18 cases (27.2%) there was a full match between the results of the prenatal diagnosis and those of the autopsy. Nine percent of fetal malformations were detected in the first trimester. The majority of malformations (72%) were detected in the second timester. Neurological malformations were the most frequent (60%), dominated by hydrocephalus and anencephaly. This study shows that, in our clinical context, even if ultrasound diagnosis is often non-exhaustive, its signs indicating the need for interruptions of pregnancy are correct. Fetopathological examination is used, in this case, to detect unknown malformations, making it possible to specify the diagnosis and to implement a strategy for subsequent pregnancies.
本研究旨在通过将产前超声诊断结果与因胎儿指征而终止妊娠的病例中的胎儿病理检查结果进行比较,评估产前超声诊断的价值。我们进行了一项回顾性描述性和分析性研究,研究时间跨度为2013年1月至2015年12月这三年。该研究涉及66例因胎儿指征而终止妊娠后进行尸检的胎儿。胎儿病理检查在63例(95.4%)中证实了超声结果。在18例(27.2%)中,产前诊断结果与尸检结果完全匹配。9%的胎儿畸形在孕早期被检测到。大多数畸形(72%)在孕中期被检测到。神经畸形最为常见(60%),以脑积水和无脑儿为主。本研究表明,在我们的临床环境中,即使超声诊断往往并不详尽,但其表明需要终止妊娠的迹象是正确的。在这种情况下,胎儿病理检查用于检测未知畸形,从而能够明确诊断并为后续妊娠制定策略。