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类风湿性血管炎会先于类风湿关节炎的诊断出现吗?

Can rheumatoid vasculitis predate a diagnosis of rheumatoid arthritis?

作者信息

Sacks Sarah, Steuer Alan

机构信息

Department of Rheumatology, Wexham Park Hospital, Slough, United Kingdom.

出版信息

Eur J Rheumatol. 2017 Mar;4(1):57-58. doi: 10.5152/eurjrheum.2017.160058. Epub 2017 Mar 1.

Abstract

We report regarding a male patient who presented with a systemic vasculitis that was consistent with a diagnosis of polyarteritis nodosa. At presentation, he had no features of inflammatory arthritis but had a high rheumatoid factor titer and low C4 level. Withdrawal of immunosuppression after 6 years resulted in the development of classical rheumatoid arthritis (RA). This case supports previous reports that revealed that vasculitis may predate the development or occur very early in the course of articular RA.

摘要

我们报告了一名男性患者,其表现出的系统性血管炎符合结节性多动脉炎的诊断。就诊时,他没有炎性关节炎的特征,但类风湿因子滴度高且C4水平低。6年后停用免疫抑制治疗导致了典型类风湿关节炎(RA)的发生。该病例支持了先前的报告,即血管炎可能在关节型RA发生之前出现或在其病程早期出现。

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本文引用的文献

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Pulmonary vasculitis as the first manifestation of rheumatoid arthritis.肺血管炎作为类风湿关节炎的首发表现。
Respir Med Case Rep. 2013 Feb 5;8:40-2. doi: 10.1016/j.rmcr.2013.01.003. eCollection 2013.
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Curr Opin Rheumatol. 2015 Jan;27(1):63-70. doi: 10.1097/BOR.0000000000000126.
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Vasculitis of the gallbladder in early rheumatoid arthritis.早期类风湿关节炎中的胆囊血管炎
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