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系统性红斑狼疮患者血细胞减少的罕见病因:自身免疫性骨髓纤维化。

A rare cause of cytopenia in a patient with systemic lupus erythematosus: Autoimmune myelofibrosis.

作者信息

Cansu Döndü Üsküdar, Teke Hava Üsküdar, Korkmaz Cengiz

机构信息

Division of Rheumatology, Department of Internal Medicine, Eskişehir Osmangazi University School of Medicine, Eskişehir, Turkey.

Division of Hematology, Department of Internal Medicine, Eskişehir Osmangazi University School of Medicine, Eskişehir, Turkey.

出版信息

Eur J Rheumatol. 2017 Mar;4(1):76-78. doi: 10.5152/eurjrheum.2016.011. Epub 2017 Mar 1.

Abstract

Hematological abnormalities are very common in the course of systemic lupus erythematosus (SLE). Myelofibrosis is a bone marrow disorder in which there is excessive fibrous tissue formation in the bone marrow. Various benign and malignant disorders can cause or be associated with a diffuse increase in the bone marrow reticular tissue. Some diseases such as infections, neoplasms, and autoimmune diseases may also induce bone marrow fibrosis (secondary myelofibrosis). Cytopenia from autoimmune myelofibrosis (AIMF) in SLE is a rare condition. Here we present a case of AIMF associated with SLE and aim to emphasize on the other cause of cytopenia in SLE.

摘要

血液学异常在系统性红斑狼疮(SLE)病程中非常常见。骨髓纤维化是一种骨髓疾病,其特征是骨髓中出现过多的纤维组织形成。各种良性和恶性疾病均可导致或与骨髓网状组织弥漫性增加相关。一些疾病,如感染、肿瘤和自身免疫性疾病,也可能诱发骨髓纤维化(继发性骨髓纤维化)。SLE中自身免疫性骨髓纤维化(AIMF)导致的血细胞减少是一种罕见情况。本文报告1例与SLE相关的AIMF病例,并旨在强调SLE中血细胞减少的其他原因。

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Autoimmune Myelofibrosis Revealing a Systemic Lupus Erythematosus.自身免疫性骨髓纤维化揭示系统性红斑狼疮
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本文引用的文献

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Haematological manifestations of lupus.狼疮的血液学表现。
Lupus Sci Med. 2015 Mar 3;2(1):e000078. doi: 10.1136/lupus-2014-000078. eCollection 2015.

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