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亚临床精索静脉曲张患者生育力低下的显著预测因素。

Significant predictive factors for subfertility in patients with subclinical varicocele.

作者信息

Chen S S-S

机构信息

Division of Urology, Taipei City Hospital Heping Fuyou Branch, National Yang-Ming University, Taipei, Taiwan.

Department of Urology, School of Medicine, National Yang-Ming University, Taipei, Taiwan.

出版信息

Andrologia. 2017 Dec;49(10). doi: 10.1111/and.12781. Epub 2017 Mar 10.

DOI:10.1111/and.12781
PMID:28295474
Abstract

We made a retrospective study to determine useful parameters for predicting subfertility in patients with subclinical varicocele (SV). One hundred and fifty men with SV and 17 age-matched men without SV were divided into three groups: Group 1, subfertile patients (n = 15); Group 2, fertile patients (n = 135); and Group 3, control patients (n = 17). Their age, body mass index (BMI), semen analysis, scrotal temperature, testicular volume, resistive index (RI), pulsatility index (PI) and peak retrograde flow (PRF) were compared. Subfertile patients (Group 1) with SV had significantly lower testicular volume and higher scrotal temperature, RI, PI and PRF than fertile men with SV (Group 2) and the control group (Group 3). Elderly men (>50 years, n = 30) with SV had a significantly higher incidence of bilateral SV than young men with SV (10/30; 33.3% vs. 12/120; 10%). There was no difference in age and BMI among the three groups. Patients with SV and RI >0.55 ml/s, PI >0.99 ml/s, total testicular volume <27 cc, scrotal temperature >34.9°C and PRF >29 cm/s have higher incidence of subfertility. Patients with SV may suffer from subfertility regardless of age. Close follow-up with colour Doppler ultrasound may be beneficial.

摘要

我们进行了一项回顾性研究,以确定预测亚临床精索静脉曲张(SV)患者生育力低下的有用参数。150例患有SV的男性和17例年龄匹配的无SV男性被分为三组:第1组,不育患者(n = 15);第2组,可育患者(n = 135);第3组,对照患者(n = 17)。比较了他们的年龄、体重指数(BMI)、精液分析、阴囊温度、睾丸体积、阻力指数(RI)、搏动指数(PI)和峰值逆流(PRF)。患有SV的不育患者(第1组)的睾丸体积明显低于患有SV的可育男性(第2组)和对照组(第3组),阴囊温度、RI、PI和PRF则更高。年龄较大(>50岁,n = 30)的患有SV的男性双侧SV的发生率明显高于年轻的患有SV的男性(10/30;33.3%对12/120;10%)。三组之间的年龄和BMI没有差异。SV患者中RI>0.55 ml/s、PI>0.99 ml/s、总睾丸体积<27 cc、阴囊温度>34.9°C和PRF>29 cm/s的不育发生率更高。患有SV的患者无论年龄大小都可能患有生育力低下。彩色多普勒超声密切随访可能有益。

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