Ghosh Palash, Dewanji Anup
Centre for Quantitative Medicine, Duke-National University of Singapore Medical School, Singapore.
Applied Statistics Unit, Indian Statistical Institute, Kolkata, India.
Pharmacoepidemiol Drug Saf. 2017 May;26(5):528-534. doi: 10.1002/pds.4191. Epub 2017 Mar 13.
The case-augmented study, in which a case sample is augmented with a reference (random) sample from the source population with only covariates information known, is becoming popular in different areas of applied science such as pharmacovigilance, ecology, and econometrics. In general, the case sample is available from some source (for example, hospital database, case registry, etc.); however, the reference sample is required to be drawn from the corresponding source population. The required minimum size of the reference sample is an important issue in this regard. In this work, we address the minimum sample size calculation and discuss related issues. Copyright © 2017 John Wiley & Sons, Ltd.
病例扩充研究，即在仅已知协变量信息的情况下，用来自源人群的对照（随机）样本扩充病例样本，在药物警戒、生态学和计量经济学等不同应用科学领域正变得越来越流行。一般来说，病例样本可从某些来源（例如医院数据库、病例登记处等）获取；然而，对照样本需要从相应的源人群中抽取。在这方面，对照样本所需的最小规模是一个重要问题。在这项工作中，我们讨论了最小样本量的计算并探讨了相关问题。版权所有© 2017约翰·威利父子有限公司。
