术中乳腺磁共振成像的可行性以及俯卧位与仰卧位在保乳手术手术规划中的作用
Feasibility of Intraoperative Breast MRI and the Role of Prone Versus Supine Positioning in Surgical Planning for Breast-Conserving Surgery.
作者信息
Mallory Melissa A, Sagara Yasuaki, Aydogan Fatih, DeSantis Stephen, Jayender Jagadeesan, Caragacianu Diana, Gombos Eva, Vosburgh Kirby G, Jolesz Ferenc A, Golshan Mehra
机构信息
Department of Surgery, Brigham and Women's Hospital/Harvard Medical School, Dana-Farber Cancer Institute, Boston, Massachusetts.
Breast Oncology Center, Dana-Farber Cancer Institute, Boston, Massachusetts.
出版信息
Breast J. 2017 Nov;23(6):713-717. doi: 10.1111/tbj.12796. Epub 2017 Mar 10.
Abstract
We assessed the feasibility of supine intraoperative MRI (iMRI) during breast-conserving surgery (BCS), enrolling 15 patients in our phase I trial between 2012 and 2014. Patients received diagnostic prone MRI, BCS, pre-excisional supine iMRI, and postexcisional supine iMRI. Feasibility was assessed based on safety, sterility, duration, and image-quality. Twelve patients completed the study; mean duration = 114 minutes; all images were adequate; no complications, safety, or sterility issues were encountered. Substantial tumor-associated changes occurred (mean displacement = 67.7 mm, prone-supine metric, n = 7). We have demonstrated iMRI feasibility for BCS and have identified potential limitations of prone breast MRI that may impact surgical planning.
摘要
我们评估了保乳手术（BCS）期间仰卧位术中磁共振成像（iMRI）的可行性，在2012年至2014年期间，我们的I期试验纳入了15名患者。患者接受了俯卧位诊断性MRI、BCS、切除前仰卧位iMRI和切除后仰卧位iMRI。基于安全性、无菌性、持续时间和图像质量评估可行性。12名患者完成了研究；平均持续时间=114分钟；所有图像均足够；未遇到并发症、安全性或无菌性问题。发生了与肿瘤相关的显著变化（平均位移=67.7毫米，俯卧位-仰卧位测量，n=7）。我们已经证明了iMRI用于BCS的可行性，并确定了俯卧位乳腺MRI可能影响手术规划的潜在局限性。
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