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北美临床正常羊驼(小羊驼)泪液分泌试验-1值的测定

Determination of Schirmer tear test-1 values in clinically normal alpacas (Vicugña pacos) in North America.

作者信息

McDonald Jessica E, Knollinger Amy M, Dees Darryl D, MacLaren Nicole E

机构信息

Eye Care for Animals, 1021 E. 3300 S., Salt Lake City, UT, 84106, USA.

Eye Care for Animals, 12419 Metric Blvd, Austin, TX, 78758, USA.

出版信息

Vet Ophthalmol. 2018 Jan;21(1):101-103. doi: 10.1111/vop.12466. Epub 2017 Mar 14.

Abstract

PURPOSE

To determine the normal reference range for Schirmer tear test-1 (STT-1) values in eyes of healthy alpacas (Vicugña pacos).

METHODS

Complete ophthalmic examinations were performed on forty healthy alpacas (80 eyes). STT-1 values were obtained in both eyes of all alpacas using a commercial STT strip of a single lot number. Data were analyzed, using a doubly repeated measures ANOVA design, Student's paired t-test, and Pearson correlation test, with P ≤ 0.05 considered significant.

RESULTS

The STT-1 values ± standard deviation (SD) were 20.80 ± 4.01 mm/min OD, 20.00 ± 4.13 mm/min OS, and 20.88 ± 4.04 mm/min OU (range 15.50-30.50 mm/min). No significant differences in STT-1 were found between OD and OS. STT-1 was not significantly affected by breed. Schirmer tear test-1 values were significantly increased by 3.45 mm/min for every 10 year increase in age.

CONCLUSIONS

This study provides a reference range of STT-1 in the healthy alpaca which can assist veterinarians in diagnosing potential keratoconjunctivitis sicca, tear film abnormalities, as well as ocular surface diseases in alpacas.

摘要

目的

确定健康羊驼(小羊驼)眼睛的泪液分泌试验-1(STT-1)值的正常参考范围。

方法

对40只健康羊驼(80只眼)进行全面的眼科检查。使用同一批号的商用STT试纸条获取所有羊驼双眼的STT-1值。采用双重复测量方差分析设计、学生配对t检验和Pearson相关检验对数据进行分析,P≤0.05认为具有统计学意义。

结果

右眼(OD)的STT-1值±标准差(SD)为20.80±4.01mm/分钟,左眼(OS)为20.00±4.13mm/分钟,双眼(OU)为20.88±4.04mm/分钟(范围15.50 - 30.50mm/分钟)。OD和OS之间的STT-1值无显著差异。STT-1不受品种的显著影响。年龄每增加10岁,Schirmer泪液分泌试验-1值显著增加3.45mm/分钟。

结论

本研究提供了健康羊驼STT-1的参考范围,可帮助兽医诊断羊驼潜在的干角结膜炎、泪膜异常以及眼表疾病。

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