Taylor W
Department of Physiological Sciences, Medical School, University, Newcastle upon Tyne, U.K.
Anticancer Res. 1987 Sep-Oct;7(5B):943-8.
World wide, millions of women have been exposed to potentially carcinogenic steroids in the form of oral contraceptives. Neoplastic liver disease has been associated with the use of such agents, but a direct causal relationship has not been proved. Oral contraceptives may protect against some diseases. Other female sex hormones used in therapeutics probably carry little hazard. Anabolic androgen use is also associated with neoplastic liver disease. Arguments are put forward for caution in the use of male and female sex hormones in man, particularly in regions where possible initiating agents (viruses, oncogenes) may be endemic.
在全球范围内，数以百万计的女性通过口服避孕药接触到了具有潜在致癌性的类固醇。肿瘤性肝病与使用此类药物有关，但尚未证实存在直接因果关系。口服避孕药可能对某些疾病有预防作用。治疗中使用的其他女性性激素可能危害较小。使用合成代谢雄激素也与肿瘤性肝病有关。有人提出，在人类使用雄性和雌性激素时应谨慎，尤其是在可能存在引发因素（病毒、癌基因）的地区。
