在接受贝伐单抗治疗的Ⅰ型黄斑毛细血管扩张症中，荧光素血管造影与光学相干断层扫描血管造影的对比研究

Fluorescein Angiography Versus Optical Coherence Tomography Angiography in Macular Telangiectasia Type I Treated With Bevacizumab Therapy.

作者信息

Yannuzzi Nicolas A, Gregori Ninel Z, Roisman Luiz, Gupta Nisha, Goldhagen Brian E, Goldhardt Raquel

出版信息

Ophthalmic Surg Lasers Imaging Retina. 2017 Mar 1;48(3):263-266. doi: 10.3928/23258160-20170301-12.

DOI:10.3928/23258160-20170301-12

Abstract

This is a report of microvascular changes seen on fluorescein angiography (FA) and optical coherence tomography angiography (OCTA) in a 47-year-old man with macular telangiectasia Type 1 (MacTel1) after a 7-year bevacizumab (Avastin; Genentech, South San Francisco, CA) treatment course. OCTA allowed for clear visualization of most telangiectasias and aneurysms in the deep capillary plexus, with only few microvascular dilatations in the superficial plexus. In addition, areas of capillary dropout in the superficial and deep vascular plexa located near telangiectasias were documented on OCTA. Serial FA demonstrated reduced number of aneurysms and telangiectasias at the 7-year mark compared to baseline. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:263-266.].

摘要

这是一份关于一名47岁1型黄斑毛细血管扩张症（MacTel1）男性患者在接受7年贝伐单抗（阿瓦斯汀；基因泰克公司，加利福尼亚州南旧金山）治疗后，荧光素血管造影（FA）和光学相干断层扫描血管造影（OCTA）所见微血管变化的报告。OCTA能够清晰显示深层毛细血管丛中的大多数毛细血管扩张和动脉瘤，而浅层丛中只有少数微血管扩张。此外，OCTA记录了位于毛细血管扩张附近的浅层和深层血管丛中的毛细血管缺失区域。与基线相比，系列FA显示在7年时动脉瘤和毛细血管扩张的数量减少。[《眼科手术、激光与视网膜成像》。2017年；48:263 - 266。]