Chen M, Wang M C, Ni R, Wang J, Wang L, Wang G N, Zhang L Y
Department of General Surgery, Lanzhou University Second Hospital, Lanzhou 730030, China; Clinical Center of Gastroenterology, Lanzhou University Second Hospital, Lanzhou 730030, China.
Department of General Surgery, Lanzhou University Second Hospital, Lanzhou 730030, China.
Zhonghua Gan Zang Bing Za Zhi. 2017 Jan 20;25(1):77-80. doi: 10.3760/cma.j.issn.1007-3418.2017.01.022.
Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases in China and manifests as simple fatty liver, non-alcoholic steatohepatitis, liver cirrhosis, and hepatocellular carcinoma. Studies have shown that intestinal flora can affect the development and progression of NAFLD via the "gut-liver axis" . Probiotics are active microorganisms with beneficial effects on the host, and more and more studies have found that probiotics play a positive role in improving NAFLD. They are cheaper, less harmful, and safer compared with antibiotics and surgery, and therefore, it may become a new method for the prevention and treatment of NAFLD. This article reviews the research advances in probiotics in the treatment of NAFLD, in order to provide a basis for the treatment of NAFLD using probiotics.
非酒精性脂肪性肝病（NAFLD）是中国最常见的慢性肝病之一，表现为单纯性脂肪肝、非酒精性脂肪性肝炎、肝硬化和肝细胞癌。研究表明，肠道菌群可通过“肠-肝轴”影响NAFLD的发生发展。益生菌是对宿主有有益作用的活性微生物，越来越多的研究发现益生菌在改善NAFLD方面发挥着积极作用。与抗生素和手术相比，它们价格更便宜、危害更小、更安全，因此可能成为预防和治疗NAFLD的新方法。本文综述了益生菌治疗NAFLD的研究进展，为应用益生菌治疗NAFLD提供依据。
