Geramizadeh B, Malek-Hosseini S A
Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran; Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Department of Surgery and hepatobiliary Surgery and Liver Transplantation, Shiraz University of Medical Sciences, Shiraz, Iran.
Int J Organ Transplant Med. 2017;8(1):1-6. Epub 2017 Feb 1.
A successful liver transplantation team consists of several specialists to work closely together. The histopathologist (anatomical pathologist) is one of the key players in this multidisciplinary team. This role starts with the pre-transplantation evaluation of the recipient's liver by diagnosis or confirming the underlying liver disease and continues with the evaluation of the explanted recipient's liver for any further information about the underlying liver disease including malignancies such as hepatocellular carcinoma, cholangiocarcinoma, or any other incidental findings. The evaluation of the new donor liver begins with determining the suitability of the donor liver for transplantation during or before the operation and continues throughout the entire post-transplantation period by evaluating not only the allograft diseases but also evaluating other tissues for infections, malignancies, . It is worthy to note that in many of the above-mentioned situations, histopathology is the gold-standard diagnostic test. In this review, we present on various tasks of a histopathologist according to the current literature and our own experience in the largest liver transplantation center in Iran.
一个成功的肝移植团队由多名专家组成，他们紧密合作。组织病理学家（解剖病理学家）是这个多学科团队的关键成员之一。这个角色始于通过诊断或确认潜在肝病对受体肝脏进行移植前评估，并在评估切除的受体肝脏时继续进行，以获取有关潜在肝病的更多信息，包括肝细胞癌、胆管癌等恶性肿瘤或任何其他偶然发现。对新供体肝脏的评估始于在手术期间或手术前确定供体肝脏是否适合移植，并在整个移植后期间持续进行，不仅要评估同种异体移植疾病，还要评估其他组织是否存在感染、恶性肿瘤等。值得注意的是，在上述许多情况下，组织病理学是金标准诊断测试。在本综述中，我们根据当前文献以及我们在伊朗最大的肝移植中心的自身经验，介绍了组织病理学家的各种任务。
