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乌干达艾滋病救助项目中接受高效抗逆转录病毒治疗(HAART)患者的抑郁症状患病率

Prevalence of Depressive Symptoms Amongst Highly Active Antiretroviral Therapy (HAART) Patients in AIDSRelief Uganda.

作者信息

Shumba Constance, Atukunda Ruth, Imakit Richard, Memiah Peter

机构信息

Uganda program, Institute of Human Virology, University of Maryland , Kampala Uganda.

Institute of Human Virology, University of Maryland , Baltimore, MD, USA.

出版信息

J Public Health Afr. 2013 Nov 26;4(2):e19. doi: 10.4081/jphia.2013.e19. eCollection 2013 Dec 3.

Abstract

There is limited data on the prevalence of depression in HIV and AIDS patients in Sub-Saharan Africa and little resources have been allocated to address this issue. Depression affects patient adherence to treatment and predisposes patients to resistance which poses a public health threat. It also affects quality of life and productivity of patients. From August 2008 to March 2009, 731 patient adherence surveys were administered to assess disease, treatment knowledge and services received. The primary variable of interest was patients' level of depressive symptoms score, constructed using factor analysis from five survey questions relating to: sadness, need to be alone, hopelessness and confusion and was categorized as (score 0), (score 1-2), (score 3-4) and (score 5-10). Majority of the patients on highly active antiretroviral therapy (HAART) (59%) were found to have depressive symptoms and this was more among women than men (66% 43%). There was some association of depressive symptoms with non-disclosure (70% of those who had not disclosed had depressive symptoms compared to 53% among those who had disclosed). There is a high prevalence of depressive symptoms among adult patients on HAART. There is need for in-depth evaluation to find out the root causes of depressive symptoms among HAART patients in AIDSRelief clinics. There is need to integrate mental health management in HIV care and treatment as well as training the existing health workers on mental health management.

摘要

关于撒哈拉以南非洲地区艾滋病毒和艾滋病患者中抑郁症患病率的数据有限,且用于解决这一问题的资源很少。抑郁症会影响患者对治疗的依从性,并使患者易产生耐药性,这对公共卫生构成威胁。它还会影响患者的生活质量和生产力。2008年8月至2009年3月,进行了731次患者依从性调查,以评估疾病、治疗知识和所接受的服务。主要关注变量是患者的抑郁症状评分水平,该评分通过对五个与悲伤、需要独处、绝望和困惑相关的调查问题进行因子分析构建而成,并分为(评分0)、(评分1 - 2)、(评分3 - 4)和(评分5 - 10)。接受高效抗逆转录病毒治疗(HAART)的患者中,大多数(59%)被发现有抑郁症状,且女性比男性更多(66%对43%)。抑郁症状与不透露病情之间存在一定关联(未透露病情的患者中有70%有抑郁症状,而透露病情的患者中这一比例为53%)。接受HAART的成年患者中抑郁症状的患病率很高。需要进行深入评估,以找出艾滋病救助诊所中接受HAART治疗的患者出现抑郁症状的根本原因。有必要将心理健康管理纳入艾滋病毒护理和治疗中,并对现有医护人员进行心理健康管理培训。

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