Wong Vincenzo K, Lubner Meghan G, Menias Christine O, Mellnick Vincent M, Kennedy Tabassum A, Bhalla Sanjeev, Pickhardt Perry J
1 Department of Radiology, Baylor College of Medicine, 1 Baylor Plaza, BCM360, Houston, TX 77030.
2 Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI.
AJR Am J Roentgenol. 2017 May;208(5):942-959. doi: 10.2214/AJR.16.16800. Epub 2017 Mar 16.
The purpose of this article is to summarize the epidemiologic characteristics, clinical aspects, and radiologic appearance of as well as the management considerations and differential diagnoses for noncutaneous primary melanomas occurring at specific anatomic sites. Primary ocular, sinonasal, meningeal, biliary, adrenal, alimentary tract, and genitourinary melanomas are highlighted.
Noncutaneous primary melanomas are a complex group of malignancies with biologic findings that are unique when compared with findings for cutaneous melanomas. Each noncutaneous primary melanoma has its own specific diagnostic and management challenges, depending on the anatomic location where they arise.
本文旨在总结特定解剖部位发生的非皮肤原发性黑色素瘤的流行病学特征、临床情况、放射学表现以及管理考量和鉴别诊断。重点关注原发性眼、鼻窦、脑膜、胆管、肾上腺、消化道和泌尿生殖系统黑色素瘤。
非皮肤原发性黑色素瘤是一组复杂的恶性肿瘤,与皮肤黑色素瘤相比,其生物学表现具有独特性。每种非皮肤原发性黑色素瘤根据其发生的解剖位置都有其特定的诊断和管理挑战。