Austin Anthony W, Pelletier Roxanne, Pilote Louise, Rabi Doreen M
Department of Social and Behavioral Sciences, University of Arkansas at Pine Bluff, Pine Bluff, Arkansas, United States of America.
Centre de psychologie Au fil des maux, Mont-Saint-Hilaire, Quebec, Canada.
PLoS One. 2017 Mar 16;12(3):e0173594. doi: 10.1371/journal.pone.0173594. eCollection 2017.
Factors associated with study completion in younger adults are not well understood. This study sought to describe psychosocial, clinical, and demographic features associated with completion of a study of men and women with premature acute coronary syndrome.
As part of the GENdEr and Sex determInantS of cardiovascular disease: From bench to beyond-Premature Acute Coronary Syndrome (GENESIS-PRAXY) study, demographic, psychosocial, and clinical variables were assessed in 1213 patients hospitalized for acute coronary syndrome (≤ 55 years; 30% women). Patients were followed for 12 months. Dropouts withdrew from the study or were lost to follow-up after 12 months; completers were still enrolled after 12 months.
Of 1213 patients initially enrolled, 777 (64.1%) completed 12-month follow-up. Fully adjusted models suggested that being older (OR = 1.04, 95% CI [1.01, 1.06]), higher subjective social status within one's country (OR = 1.11, 95% CI [1.01, 1.22]), being free of type II diabetes, (OR = 0.66, 95% CI [0.45, 0.97]), non-smoking status (OR = 0.70, 95% CI [0.51, 0.95]) and being free of depression (OR = 1.52, 95% CI [1.11, 2.07]) were independently associated with study completion.
Recruitment/retention strategies targeting individuals who smoke, are younger, have low subjective social status within one's country, have diabetes, or have depression may improve participant follow-up in cardiovascular cohort studies.
与年轻成年人完成研究相关的因素尚未得到充分了解。本研究旨在描述与过早急性冠状动脉综合征的男性和女性完成一项研究相关的心理社会、临床和人口统计学特征。
作为心血管疾病的性别和性别决定因素：从实验台到超越——过早急性冠状动脉综合征（GENESIS-PRAXY）研究的一部分，对1213名因急性冠状动脉综合征住院的患者（≤55岁；30%为女性）的人口统计学、心理社会和临床变量进行了评估。对患者进行了12个月的随访。退出者退出了研究或在12个月后失访；完成者在12个月后仍在研究中。
在最初纳入的1213名患者中，777名（64.1%）完成了12个月的随访。完全调整模型表明，年龄较大（OR = 1.04，95%CI[1.01，1.06]）、在本国的主观社会地位较高（OR = 1.11，95%CI[1.01，1.22]）、没有II型糖尿病（OR = 0.66，95%CI[0.45，0.97]）、非吸烟状态（OR = 0.70，95%CI[0.51，0.95]）和没有抑郁症（OR = 1.52，95%CI[1.11，2.07]）与研究完成独立相关。
针对吸烟、年轻、在本国主观社会地位低、患有糖尿病或患有抑郁症的个体的招募/保留策略可能会改善心血管队列研究中的参与者随访情况。
