Chatterjee S N, Agarwal S
Biophysics Division, Saha Institute of Nuclear Physics, Calcutta, India.
Free Radic Biol Med. 1988;4(1):51-72. doi: 10.1016/0891-5849(88)90011-1.
This article describes the properties, production and characterization of liposomes with special reference to their use as membrane model for the study of lipid peroxidation. It presents briefly the methods that can be used for the assay of liposomal lipid peroxidation and brings out the special advantages these liposomes provide in elucidating the mechanism of lipid peroxidation by different physical and chemical agents. Studies involving liposomal lipid peroxidation by different agents and the consequent changes in the structure and function of liposomal membrane have been reviewed briefly.
本文描述了脂质体的性质、制备及特性,特别提及了其作为膜模型用于研究脂质过氧化的用途。简要介绍了可用于测定脂质体脂质过氧化的方法,并阐述了这些脂质体在阐明不同物理和化学试剂引发脂质过氧化机制方面所具有的特殊优势。本文还简要综述了有关不同试剂引发脂质体脂质过氧化以及脂质体膜结构与功能随之发生变化的研究。