Boyvat Fatih
Department of Interventional Radiology, Baskent University, Ankara, Turkey.
Exp Clin Transplant. 2017 Mar;15(Suppl 2):25-30. doi: 10.6002/ect.TOND16.L8.
The current treatment modalities for patients with hepatocellular carcinoma are discussed in this review. Hepatocellular carcinoma arises in up to 90% of cirrhotic patients, mainly due to chronic viral hepatitis and alcohol abuse. Nearly two-thirds of all patients with hepatocellular carcinoma are diagnosed at advanced stages, thus causing problems with treatment. Regardless of the stage of the disease, interventional radiology offers both curative and palliative treatment options in the management of this disease. Selecting the most appropriate treatment requires an initial staging assessment and detailed clinical and radiologic workup. Treatment allocation is based on liver function, size and number of tumors, macrovascular invasion, and extrahepatic spread of disease.
本综述讨论了肝细胞癌患者目前的治疗方式。肝细胞癌在高达90%的肝硬化患者中发生，主要归因于慢性病毒性肝炎和酒精滥用。几乎三分之二的肝细胞癌患者在晚期被诊断出来，从而导致治疗困难。无论疾病处于何种阶段，介入放射学在该疾病的管理中都提供了治愈性和姑息性的治疗选择。选择最合适的治疗方法需要进行初步分期评估以及详细的临床和影像学检查。治疗方案的分配基于肝功能、肿瘤的大小和数量、大血管侵犯以及疾病的肝外扩散情况。
