Dasgupta J D, Singh Udai N
Molecular Biology Unit, Tata Institute of Fundamental Research, Homi Bhabha Road, Colaba, 400005, Bombay, India.
Wilehm Roux Arch Dev Biol. 1982 Nov;191(6):378-380. doi: 10.1007/BF00879627.
The distribution of gap junctions in zebra fish embryo is a dynamic process. They appear during cleavage stages and are uniformly distributed between deep cells in early blastula. By mid-blastula stage their density increases all over the embryo. At this stage lightly stained L cells and densely stained D cells (Dasgupta and Singh 1981; Wilhelm Roux's Arch Dev Biol 190:358) develop some differences in their surface properties due to which the frequencies of gap junctions between homologous (L-L and D-D) cells are two- to threefold higher than between heterologous (L-D) cells. Before the initiation of epipoly the gap junction occurrence increases in the envelopinglayer (EVL) and then decreases. The possible functional significance of the organization of these junctions is discussed.
斑马鱼胚胎中缝隙连接的分布是一个动态过程。它们在卵裂期出现,并均匀分布于早期囊胚的深层细胞之间。到囊胚中期,其密度在整个胚胎中增加。在这个阶段,轻度染色的L细胞和重度染色的D细胞(Dasgupta和Singh,1981年;《Wilhelm Roux's Arch Dev Biol》190:358)在表面特性上出现了一些差异,因此同源(L-L和D-D)细胞之间缝隙连接的频率比异源(L-D)细胞之间高两到三倍。在表皮外包开始之前,缝隙连接在包被层(EVL)中的出现先增加然后减少。文中讨论了这些连接组织可能的功能意义。