外源性环磷酸腺苷可阻断原肠胚形成期鸡胚细胞中由毒蕈碱受体介导的细胞内钙释放。
Exogeneous cyclic AMP blocks the muscarinic receptor-mediated intracellular Ca-release in the gastrulating chick embryo cells.
作者信息
Laasberg Tiit
机构信息
Institute of Chemical Physics and Biophysics, Estonian Academy of Sciences, USSR.
出版信息
Rouxs Arch Dev Biol. 1987 Oct;196(7):464-466. doi: 10.1007/BF00399147.
PMID:28305395
Abstract
Exogeneous cyclic AMP (cAMP, 10M), when added together with acetylcholine (ACh, 500 μM) to dissociated chick embryo cells, blocked the ACh-stimulated increase in the level of cytosolic free Ca ([Ca]). This inhibiting action of exogeneous cAMP is probably mediated by intracellular cyclic GMP (cGMP) and cAMP.
摘要
当将外源性环磷酸腺苷（cAMP，10微摩尔）与乙酰胆碱（ACh，500微摩尔）一起添加到解离的鸡胚细胞中时，可阻断ACh刺激引起的细胞质游离钙（[Ca]）水平升高。外源性cAMP的这种抑制作用可能是由细胞内环磷酸鸟苷（cGMP）和cAMP介导的。
Zotero 插件