Greger Valerie, Berking Stefan
Zoologisches Institut der Universität zu Köln, Weyertal 119, W-5000, Köln, Federal Republic of Germany.
Rouxs Arch Dev Biol. 1991 Sep;200(4):234-236. doi: 10.1007/BF00361343.
The tumour-promoting phorbol ester 12-O-tetradecanoylphorbol 13-acetate (TPA) interfers with nerve cell production in Hydra when applied to the animals' culture medium. Precursor cells exposed to 0.2 nM TPA during the first half of their S-phase are prevented from differentiating into nerve cells. Precursor cells which start their S-phase following a treatment with TPA give rise to nerve cells. The frequency is higher than in untreated control animals.
促肿瘤佛波酯12 - O -十四烷酰佛波醇13 - 乙酸酯（TPA）应用于水螅的培养基时，会干扰其神经细胞的产生。在前体细胞S期的前半段暴露于0.2 nM TPA会阻止它们分化为神经细胞。经TPA处理后开始S期的前体细胞会产生神经细胞。其频率高于未处理的对照动物。
