Wright J R, Kyriakos M, DeSchryver-Kecskemeti K
Department of Pathology, Washington University School of Medicine, St. Louis, MO.
Arch Pathol Lab Med. 1988 Mar;112(3):251-8.
An example of malignant fibrous histiocytoma (MFH) of the stomach, manifesting initially as a pulmonary metastasis, is described. A review of the world medical literature yielded ten other examples of MFH of the alimentary tract--four in the large intestine, two each in the small intestine and rectum, and one each in the esophagus and stomach. Patients ranged in age from 17 to 74 years, and all but one were males. Histologically, 91% of the tumors were of the pleomorphic type, with or without an associated storiform pattern. Six of the 11 patients died, two postoperatively and four with tumor, while the others were alive from 14 months to eight years after therapy. The distinction between gastric MFH and leiomyosarcoma is discussed.
本文描述了一例最初表现为肺转移的胃恶性纤维组织细胞瘤（MFH）。回顾世界医学文献发现，消化道MFH还有其他10例——4例发生在大肠，小肠和直肠各2例，食管和胃各1例。患者年龄在17至74岁之间，除1例女性外均为男性。组织学上，91%的肿瘤为多形性类型，伴有或不伴有相关的束状模式。11例患者中有6例死亡，2例术后死亡，4例死于肿瘤，其余患者在治疗后存活14个月至8年。文中还讨论了胃MFH与平滑肌肉瘤的鉴别。
