Butler W T, Munksgaard E C, Richardson W S
J Dent Res. 1979 Mar;58(Spec Issue B):817-24. doi: 10.1177/00220345790580023301.
One of the most abundant noncollagenous proteins of dentin is a phosphoprotein rich in aspartic acid and phosphoserine. This protein occurs in soluble and inextractable forms, the latter being associated with the insoluble collagenous matrix. This protein is capable of tightly binding a relatively high level of calcium. Biosynthetic and radioautographic data suggest that shortly after its biosynthesis, the phosphoprotein is transported and bound to the collagen at the predentin-dentin junction. This event is probably central to the mineralization process, though other glycoproteins may be involved.
牙本质中最丰富的非胶原蛋白之一是一种富含天冬氨酸和磷酸丝氨酸的磷蛋白。这种蛋白质以可溶和不可提取两种形式存在，后者与不溶性胶原基质相关。这种蛋白质能够紧密结合相对高水平的钙。生物合成和放射自显影数据表明，磷蛋白在生物合成后不久就被转运并结合到前期牙本质 - 牙本质交界处的胶原上。尽管可能涉及其他糖蛋白，但这一事件可能是矿化过程的核心。
