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孟加拉国2型糖尿病成年人糖尿病慢性并发症的发生率、模式及其与血糖控制的关系。

Frequency and pattern of chronic complications of diabetes and their association with glycemic control among adults with type 2 diabetes in Bangladesh.

作者信息

Selim Shahjada

机构信息

Department of Endocrinology & Metabolism, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka 1000, Bangladesh.

出版信息

Diabetes Metab Syndr. 2017 Nov;11 Suppl 1:S329-S332. doi: 10.1016/j.dsx.2017.03.010. Epub 2017 Mar 7.

DOI:10.1016/j.dsx.2017.03.010
PMID:28314538
Abstract

BACKGROUND

The study was conducted in diabetes care centers to explore association of chronic complications of diabetes with glycemic status along with their frequency and pattern among adult patients with type 2 diabetes.

METHODS

A cross-sectional study was conducted at outpatient departments of eight diabetes care centers in Dhaka. Data were collected by face to face interview by trained research physicians. Disease related information was recorded in the checklist from diabetes guide books of the patients. Chronic complications of diabetes were recorded from the records of expert consultation.

RESULTS

Records of 5215 patients with type diabetes (59.4% males) were analyzed. Mean age of the male and female subjects was 52.7 and 50.6 years, respectively. Hypertriglyceridemia [OR 1.74, 95% CI (1.18-2.57)], increased LDL [OR 1.27, 95% CI (0.78-2.07)] and decreased HDL [OR 0.81, 95% CI (0.43-1.53)] and diabetic foot ulcers [OR 2.32, 95% CI (1.14-4.01)] were significantly associated with poor glycemic control, whereas hypertriglyceridemia [OR 2.39, 95% CI (1.42-4.03)] diabetic foot ulcer [OR 2.32, 95% CI (1.14-4.01)], hypetension [OR 1.65, 95% CI (1.15-2.43)] and coronary artery diasease [OR 1.23, 95% CI (0.77-2.13) were significantly associated with poor glycemic control according to FPG.

CONCLUSION

The study finds association of chronic complications of diabetes with glycemic control among type 2 diabetes patients in Bangladesh.

摘要

背景

该研究在糖尿病护理中心开展,旨在探讨2型糖尿病成年患者中糖尿病慢性并发症与血糖状态的关联以及其发生频率和模式。

方法

在达卡的8个糖尿病护理中心的门诊部进行了一项横断面研究。数据由经过培训的研究医生通过面对面访谈收集。疾病相关信息记录在患者糖尿病指南手册的检查表中。糖尿病慢性并发症从专家会诊记录中获取。

结果

分析了5215例2型糖尿病患者(男性占59.4%)的记录。男性和女性受试者的平均年龄分别为52.7岁和50.6岁。高甘油三酯血症[比值比(OR)1.74,95%置信区间(CI)(1.18 - 2.57)]、低密度脂蛋白升高[OR 1.27,95% CI(0.78 - 2.07)]、高密度脂蛋白降低[OR 0.81,95% CI(0.43 - 1.53)]和糖尿病足溃疡[OR 2.32,95% CI(1.14 - 4.01)]与血糖控制不佳显著相关,而根据空腹血糖(FPG),高甘油三酯血症[OR 2.39,95% CI(1.42 - 4.03)]、糖尿病足溃疡[OR 2.32,95% CI(1.14 - 4.01)]、高血压[OR 1.65,95% CI(1.15 - 2.43)]和冠状动脉疾病[OR 1.23,95% CI(0.77 - 2.13)]与血糖控制不佳显著相关。

结论

该研究发现孟加拉国2型糖尿病患者中糖尿病慢性并发症与血糖控制之间存在关联。

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