John Walls Renal Unit, University Hospitals of Leicester, Leicester, UK.
Imperial College Renal and Transplant Centre, Hammersmith Hospital, London, UK.
Kidney Int. 2017 Apr;91(4):784-786. doi: 10.1016/j.kint.2017.01.022.
The impact of dialysis on cognitive trends is uncertain. Kurella Tamura et al. evaluated cognitive trajectories in 212 participants from the Chronic Renal Insufficiency Cohort study and found that dialysis initiation was associated with a decline in executive function. This is consistent with a cerebrovascular basis for cognitive impairment in patients with renal disease. However, larger corroborative studies are needed while targets for intervention are identified to ameliorate dialytic effects on cognitive function.
透析对认知趋势的影响尚不确定。Kurella Tamura 等人评估了慢性肾功能不全队列研究中的 212 名参与者的认知轨迹，发现透析开始与执行功能下降有关。这与肾脏病患者认知障碍的脑血管基础一致。然而，需要进行更大的验证性研究，同时确定干预目标，以减轻透析对认知功能的影响。
