Sporn M B, Roberts A B
Laboratory of Chemoprevention, National Cancer Institute, Bethesda, Maryland 20892.
Nature. 1988 Mar 17;332(6161):217-9. doi: 10.1038/332217a0.
The actions of many peptide growth factors include both stimulation and inhibition of cell proliferation, as well as effects unrelated to the control of cell growth. One peptide can have both stimulatory and inhibitory activity in a single cell, depending on the context of the other signal molecules present.
许多肽生长因子的作用包括刺激和抑制细胞增殖，以及与细胞生长控制无关的效应。一种肽在单个细胞中可以同时具有刺激和抑制活性，这取决于所存在的其他信号分子的背景情况。
