Fellow in Endocrinology and Metabolism, NYU School of Medicine, New York, NY, USA.
Division of Endocrinology and Metabolism, NYU Langone Medical Center, 522 1st Ave, Smilow 707B, New York, NY, 10016-6402, USA.
Osteoporos Int. 2017 Jun;28(6):1805-1816. doi: 10.1007/s00198-017-3952-0. Epub 2017 Mar 17.
Transient osteoporosis of the hip (TOH) is a temporary clinical condition of unknown etiology which usually resolves with conservative therapy though may be complicated by fracture or progression to avascular necrosis (AVN). TOH may be slightly more prevalent in men but when it occurs in women, it is most often seen in the latter part of pregnancy. Though fracture is a rare complication of TOH when it occurs, it is most often associated with TOH occurring in pregnancy. Magnetic resonance imaging (MRI) is the best method to diagnosis TOH. Low signal intensity on T1-weighted images, high signal intensity on T2-weighted images, and homogenous pattern of edema (the femoral head and/or neck) with normal subchondral area are in favor of TOH. A shortened course to recovery is reported by use of bisphosphonates, calcitonin, or teriparatide. Based on reported cases, core decompression is not superior to medical therapy. Transient osteoporosis of the hip, which often has no known etiology, usually resolves with conservative therapy but may predispose the patient to fracture or avascular necrosis. Diagnostic method of choice is magnetic resonance imaging. Bisphosphonates, calcitonin, or teriparatide are reported as a useful approach to reduce duration of recovery.
髋关节一过性骨质疏松症(TOH)是一种病因不明的暂时性临床病症,通常采用保守治疗即可痊愈,但可能会并发骨折或进展为缺血性坏死(AVN)。TOH 在男性中略为多见,但在女性中,其最常发生于妊娠后期。虽然 TOH 并发骨折较为罕见,但最常与妊娠相关。磁共振成像(MRI)是诊断 TOH 的最佳方法。T1 加权图像低信号强度、T2 加权图像高信号强度以及均匀性水肿模式(股骨头和/或颈部)伴正常软骨下区域均提示 TOH。使用双膦酸盐、降钙素或特立帕肽可缩短恢复时间。基于已报道的病例,骨芯减压术并不优于药物治疗。髋关节一过性骨质疏松症的病因通常不明确,通常采用保守治疗即可痊愈,但可能使患者易于发生骨折或缺血性坏死。首选的诊断方法是磁共振成像。双膦酸盐、降钙素或特立帕肽被报道为一种有用的方法,可以缩短恢复时间。