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[妊娠期髋关节短暂性骨质疏松症。降钙素治疗成功:病例报告]

[Transient osteoporosis of the hip in pregnancy. Successful treatment with calcitonin: a case report].

作者信息

Laktasic-Zerjavic N, Curkovic B, Babic-Naglic D, Potocki K, Prutki M, Soldo-Juresa D

机构信息

University Department of Rheumatology, Zagreb University Hospital Center, Kispaticeva 12, 10000 Zagreb, Kroatien.

出版信息

Z Rheumatol. 2007 Oct;66(6):510-3. doi: 10.1007/s00393-007-0191-3.

Abstract

Transient osteoporosis of the hip is a rare clinical disorder of unknown etiology, characterized by hip pain and functional disability that resolves spontaneously in 6-24 months. Despite a benign prognosis, the long clinical course causes prolonged disability. We report on a case of transient osteoporosis of the hip during pregnancy that was rapidly resolved with the use of calcitonin. An accurate diagnosis was made 2 months after the onset of symptoms (4 weeks postpartum) based on findings in the form of bone marrow edema of the right hip by magnetic resonance imaging. The patient received calcitonin for 8 weeks and the beneficial effect was observed after 3 weeks of therapy with full resolution of symptoms after 8 weeks of therapy (4 months after onset of symptoms). We suggest that the use of calcitonin may be considered as a therapeutic intervention to shorten the disease duration.

摘要

髋部短暂性骨质疏松症是一种病因不明的罕见临床病症,其特征为髋部疼痛和功能障碍,6至24个月内可自行缓解。尽管预后良好,但临床病程较长会导致残疾时间延长。我们报告一例妊娠期间发生的髋部短暂性骨质疏松症病例,使用降钙素后迅速缓解。根据磁共振成像显示的右髋骨髓水肿表现,在症状出现2个月后(产后4周)做出了准确诊断。患者接受了8周的降钙素治疗,治疗3周后观察到有益效果,治疗8周后(症状出现4个月后)症状完全缓解。我们建议可以考虑使用降钙素作为一种治疗干预措施来缩短病程。

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