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[脊髓损伤患者下尿路功能障碍的神经泌尿学诊断与治疗:德语区截瘫医学协会(DMGP)S2k指南,德国医学质量与效率研究所登记号179/001]

[Neuro-urological diagnosis and therapy of lower urinary tract dysfunction in patients with spinal cord injury : S2k Guideline of the German-Speaking Medical Society of Paraplegia (DMGP), AWMF register no. 179/001].

作者信息

Böthig R, Domurath B, Kaufmann A, Bremer J, Vance W, Kurze I

机构信息

Abt. Neuro-Urologie, Querschnittgelähmtenzentrum, BG-Klinikum Hamburg, Bergedorfer Str. 10, 21033, Hamburg, Deutschland.

Neurologische Rehabilitationsklinik, Neuro-Urologisches Zentrum, Kliniken Beelitz GmbH, Paracelsusring 6a, 14547, Beelitz-Heilstätten, Deutschland.

出版信息

Urologe A. 2017 Jun;56(6):785-792. doi: 10.1007/s00120-017-0354-z.

Abstract

BACKGROUND

Most patients with spinal cord injury (SCI) suffer from neurogenic lower urinary tract dysfunction (NLUTD), bowel dysfunction and sexual dysfunction. If these remain untreated, severe medical complications and serious limitations (restrictions) in quality of life are imminent.

OBJECTIVES

In the long term, there are considerable differences in the treatment results of highly specialized centers versus other treatment facilities.

MATERIALS AND METHODS

Against this background, a consensus-based guideline, according to the AWMF (Association of the Scientific Medical Societies in Germany) criteria (S2k), was developed by the neuro-urology working group of the DMPG (German-Speaking Medical Society of Paraplegia).

RESULTS

The guideline defines the principles and objectives of the neuro-urological care of patients with SCI and discusses in detail the principles of diagnosis and therapy of NLUTD. The need for video-urodynamic studies as a basis for the classification of the NLUTD and as a foundation for the development of a treatment strategy is emphasized. Both conservative and surgical therapy options and their indications are explained in detail. Possible complications and their prevention in the long-term course of SCI are presented with a particular consideration of the specific features of urinary tract infections and autonomic dysreflexia. Finally, the principles of the provision of urological appliances are discussed.

CONCLUSIONS

The presented S2k guideline provides the current standards in the neuro-urological care of patients with NLUTD due to SCI. Their consistent implementation both in the acute and chronic phase as well as in the context of lifelong surveillance of SCI patients should prevent the impending complications of NLUTD.

摘要

背景

大多数脊髓损伤(SCI)患者患有神经源性下尿路功能障碍(NLUTD)、肠道功能障碍和性功能障碍。如果这些问题得不到治疗,严重的医学并发症和生活质量的严重受限将很快出现。

目的

从长期来看,高度专业化中心与其他治疗机构的治疗结果存在相当大的差异。

材料与方法

在此背景下,德国截瘫患者德语医学协会(DMPG)的神经泌尿学工作组根据德国科学医学协会联盟(AWMF)标准(S2k)制定了一项基于共识的指南。

结果

该指南定义了SCI患者神经泌尿护理的原则和目标,并详细讨论了NLUTD的诊断和治疗原则。强调了视频尿动力学研究作为NLUTD分类基础和制定治疗策略基础的必要性。详细解释了保守和手术治疗方案及其适应症。介绍了SCI长期病程中可能出现的并发症及其预防措施,特别考虑了尿路感染和自主神经反射异常的具体特征。最后,讨论了提供泌尿外科器具的原则。

结论

所提出 的S2k指南提供了因SCI导致的NLUTD患者神经泌尿护理的当前标准。在急性期和慢性期以及对SCI患者进行终身监测的过程中持续实施这些标准,应可预防即将出现的NLUTD并发症。

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