Department of Gynecology, Instituto Nacional de Cancerología, Mexico.
Clinical Research, Instituto Nacional de Cancerología, Mexico City, Mexico.
Int J Surg. 2017 May;41:1-5. doi: 10.1016/j.ijsu.2017.03.023. Epub 2017 Mar 14.
According to the International Federation of Gynecology and Obstetrics (FIGO) guidelines, every patient diagnosed with ovarian cancer (OC) should undergo a complete staging procedure to adequately assess tumor spread. The role of lymphadenectomy in the initial management of primary early mucinous ovarian cancer (MOC) remains unclear.
To describe the prevalence of pelvic and para-aortic node metastases in MOC.
The records of patients with MOC treated at our Institute during January 2005 to December 2011 were assessed. A descriptive and comparative analysis was conducted. Overall survival (OS) and diseases-free period (DFP) were calculated with the Kaplan-Meier method and were compared with the log-rank test.
Of 31 patients with MOC, 14 (45.16%) underwent lymphadenectomy, obtaining 190 pelvic nodes, with a median of 9 pelvic lymph nodes removed per patient (interquartile range = 15). There was no evidence of metastatic disease in the dissected pelvic nodes.
These results suggest that complete surgical staging with lymph node dissection has no effect on recurrence, disease-free period, and overall survival of patients with early stage MOC.
根据国际妇产科联合会（FIGO）指南，每一位被诊断为卵巢癌（OC）的患者都应接受全面的分期手术，以充分评估肿瘤的扩散情况。淋巴结切除术在原发性早期黏液性卵巢癌（MOC）的初始治疗中的作用仍不清楚。
描述 MOC 患者盆腔和腹主动脉旁淋巴结转移的发生率。
评估了我院 2005 年 1 月至 2011 年 12 月期间治疗的 MOC 患者的记录。进行了描述性和对比分析。采用 Kaplan-Meier 法计算总生存率（OS）和无病生存期（DFP），并采用对数秩检验进行比较。
在 31 例 MOC 患者中，14 例（45.16%）接受了淋巴结切除术，共获得 190 个盆腔淋巴结，每个患者平均切除 9 个盆腔淋巴结（四分位距=15）。在切除的盆腔淋巴结中未发现转移性疾病。
这些结果表明，对于早期 MOC 患者，完整的手术分期伴淋巴结清扫术对复发、无病生存期和总生存期没有影响。
