Di H P, Niu X H, Li Q, Li X L, Xue J D, Cao D Y, Han D W, Xia C D
Department of Burns, Zhengzhou First People's Hospital, Zhengzhou 450004, China.
Zhonghua Shao Shang Za Zhi. 2017 Mar 20;33(3):156-159. doi: 10.3760/cma.j.issn.1009-2587.2017.03.006.
To investigate the effect of Meek skin grafting on patients with extensive deep burn at different age groups. Eighty-four patients with extensive deep burns conforming to the study criteria were hospitalized in our unit from April 2011 to April 2015. Patients were divided into children group (C, with age less than 12 years old), young and middle-aged group (YM, with age more than 18 years and less than 50 years old), and old age group (O, with age more than 55 years old) according to age, with 28 patients in each group. All patients received Meek skin grafting treatment. The use of autologous skin area, operation time, wound healing time, and hospitalization time were recorded. The survival rate of skin graft on post operation day 7, complete wound healing rate in post treatment week 2, and the mortality were calculated. Data were processed with one-way analysis of variance, test, and (2) test. The use of autologous skin area of patients in group C was (5.1±1.0)% total body surface area (TBSA), significantly less than (8.3±1.0)%TBSA and (8.3±1.4)%TBSA in groups YM and O, respectively (with values 32.900 and 52.624, respectively, values below 0.05). The operation time, wound healing time, and hospitalization time of patients in group C were (1.368±0.562) h, (9.6±0.6) and (32±11) d, significantly shorter than those in group YM [(3.235±0.011) h, (16.9±2.6) and (48±12) d, respectively] and group O [(3.692±0.481) h, (17.3±2.6) and (46±13) d, respectively, with values from 4.350 to 21.160, values below 0.05]. The survival rate of skin graft of patients on post operation day 7 in group C was (92±15)%, significantly higher than (81±10)% and (72±12)% in groups YM and O, respectively (with values 5.509 and 3.229, respectively, values below 0.05). The above indexes in groups YM and O were similar (with values from 0.576 to 22.958, values above 0.05). Complete wound healing rate in post treatment week 2 and the mortality of patients in group C were similar to those in groups YM and O (with (2) values 0.365 and 0.122, respectively, values above 0.05). Meek skin grafting can be used in the treatment of patients with extensive deep burns at different age groups, compared with the young and middle-aged and old patients, the effect in children was better.
探讨Meek植皮术对不同年龄组大面积深度烧伤患者的治疗效果。2011年4月至2015年4月，我科收治符合研究标准的大面积深度烧伤患者84例。根据年龄将患者分为儿童组（C组，年龄＜12岁）、中青年组（YM组，年龄＞18岁且＜50岁）和老年组（O组，年龄＞55岁），每组28例。所有患者均接受Meek植皮治疗。记录自体皮使用面积、手术时间、创面愈合时间及住院时间。计算术后第7天植皮成活率、治疗后第2周创面完全愈合率及死亡率。数据采用单因素方差分析、检验和（2）检验进行处理。C组患者自体皮使用面积为（5.1±1.0）%体表面积（TBSA），明显低于YM组的（8.3±1.0）%TBSA和O组的（8.3±1.4）%TBSA（值分别为32.900和52.624，值均＜0.05）。C组患者手术时间、创面愈合时间及住院时间分别为（1.368±0.562）h、（9.6±0.6）d和（32±11）d，明显短于YM组[分别为（3.235±0.011）h、（16.9±2.6）d和（48±12）d]和O组[分别为（3.692±0.481）h、（17.3±2.6）d和（46±13）d，值为4.350至21.160，值均＜0.05]。C组患者术后第7天植皮成活率为（92±15）%，明显高于YM组的（81±10）%和O组的（72±12）%（值分别为5.509和3.229，值均＜0.05）。YM组和O组上述指标相似（值为0.576至22.958，值均＞0.05）。C组患者治疗后第2周创面完全愈合率及死亡率与YM组和O组相似（（2）值分别为0.365和0.122，值均＞0.05）。Meek植皮术可用于不同年龄组大面积深度烧伤患者的治疗，与中青年及老年患者相比，儿童患者效果更佳。
