Grimes Pearl E, Nashawati Rama
Vitiligo & Pigmentation Institute of Southern California, 5670 Wilshire Boulevard #650, Los Angeles, CA 90036, USA; Division of Dermatology, David Geffen School of Medicine, University of California, Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA.
Vitiligo & Pigmentation Institute of Southern California, 5670 Wilshire Boulevard #650, Los Angeles, CA 90036, USA.
Dermatol Clin. 2017 Apr;35(2):219-227. doi: 10.1016/j.det.2016.11.010.
The general goals of medical management of vitiligo are to repigment vitiliginous areas of skin and to stabilize the progression of depigmentation. However, for some patients with vitiligo affecting extensive body surface areas who are unresponsive to repigmentation therapies, depigmentation of the remaining normal skin may be a better choice. Candidates for depigmentation therapy should be carefully screened and patient education is essential. Permanent topical therapies used for depigmentation include monobenzyl ether of hydroquinone, 4-methoxyphenol, and 88% phenol. Physical modalities, such as cryotherapy and lasers, are also being used successfully.
白癜风医学治疗的总体目标是使白癜风皮肤区域重新色素沉着，并稳定色素脱失的进展。然而，对于一些白癜风累及大面积体表区域且对色素再生疗法无反应的患者，使剩余正常皮肤色素脱失可能是更好的选择。色素脱失疗法的候选者应仔细筛选，患者教育至关重要。用于色素脱失的永久性局部疗法包括对苯二酚单苄醚、4-甲氧基苯酚和88%苯酚。冷冻疗法和激光等物理方法也在成功应用。
